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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: Neurobiol Aging. 2023 Jul 17;131:182–195. doi: 10.1016/j.neurobiolaging.2023.07.007

Figure 5. Cytoskeleton Rearrangement Assay of Neuronal Precursor Cells and iPSC-Derived Neurons.

Figure 5.

A. Representative images of D30 neuron progenitor cells. Blue: Nuclear counterstain DAPI, Green: Actin filament stain Phalloidin. Scale Bars: 125 μm B. Representative images of D70 neurons. Blue: Nuclear counterstain DAPI, Green: Actin filament stain Phalloidin, Red: β-tubulin 3. Scale Bars: 125 μm C-D. Comparison of cytoskeleton characteristics that were significantly different between D30 (C-D) and D70 (E-F) TTC3 pS1038C cells and unedited cells after treatment with Cytochalasin D (CytoD), Jasplakinolide (Jaspla) and Y27632. Ch1: Phalloidin, Ch3: β-tubulin 3. *: p-value<0.05, ***: p-value<0.001.