Table 1.
Characteristics (number and percent unless otherwise specified) of antiretroviral therapy-naïve persons who enrolled in the Center for AIDS Clinical Research Network of Integrated Clinical Systems, 2011–2019, and who self-reported alcohol consumption within 1 year of enrollment, stratified by alcohol usea
| Baseline alcohol use | Total | |||
|---|---|---|---|---|
| No use | Moderate | Unhealthy | ||
| N | 448 | 662 | 671 | 1781 |
| Demographics | ||||
| Men (gender) | 348 (78) | 585 (88) | 589 (88) | 1522 (86) |
| Ageb | 41 (30, 51) | 35 (27, 45) | 32 (27, 43) | 35 (28, 46) |
| Race | ||||
| Black | 181 (40) | 267 (40) | 187 (28) | 635 (36) |
| White | 233 (52) | 316 (48) | 410 (61) | 959 (54) |
| Other | 34 (7) | 79 (12) | 74 (11) | 187 (11) |
| Hispanic ethnicity | 75 (17) | 79 (12) | 134 (20) | 288 (16) |
| HIV Risk Factor | ||||
| Heterosexual | 144 (32) | 121 (18) | 107 (16) | 372 (21) |
| IDU | 34 (8) | 15 (2) | 28 (4) | 77 (4) |
| MSM | 205 (46) | 470 (71) | 479 (71) | 1154 (65) |
| MSM + IDU | 36 (8) | 38 (6) | 36 (5) | 110 (6) |
| Other/Unknown | 29 (7) | 18 (3) | 21 (3) | 68 (4) |
| Calendar year of enrollmentb | 14 (12, 15) | 13 (12, 15) | 14 (12, 15) | 13 (12, 15) |
| Clinical variables | ||||
| Viral load [log10 copies/mL] | 4.7 (4.1, 5.2) | 4.7 (4.1, 5.2) | 4.6 (4.0, 5.1) | 4.6 (4.1, 5.1) |
| Missing | 32 (7) | 35 (5) | 44 (7) | 111 (6) |
| CD4 cell countb | 304 (109, 527) | 369 (180, 548) | 391 (237, 558) | 367 (182, 551) |
| Missing | 25 (6) | 32 (5) | 31 (5) | 88 (5) |
| Creatinine [mg/dL] | 0.9 (0.8, 1.0) | 0.9 (0.8, 1.0) | 0.9 (0.8, 1.0) | 0.9 (0.8, 1.0) |
| Missing | 59 (13) | 85 (13) | 82 (12) | 226 (13) |
| Hemoglobin [g/dL] | 13.2 (11.6, 14.4) | 14.0 (12.7, 15.0) | 14.3 (13.3, 15.2) | 14.0 (12.6, 15.0) |
| Missing | 65 (15) | 84 (13) | 92 (14) | 241 (14) |
| FIB-4 | 1.0 (0.7, 1.5) | 0.8 (0.6, 1.2) | 0.8 (0.6, 1.2) | 0.9 (0.6, 1.3) |
| Missing | 89 (20) | 142 (21) | 123 (18) | 354 (20) |
| BMI | 25.4 (22.6, 28.4) | 24.8 (22.2, 28.2) | 24.6 (22.2, 27.7) | 24.8 (22.3, 28.0) |
| Missing | 192 (43) | 314 (47) | 250 (37) | 756 (42) |
| Albumin [g/dl] | 4.1 (3.7, 4.4) | 4.2 (3.9, 4.5) | 4.4 (4.0, 4.6) | 4.2 (3.9, 4.5) |
| Missing | 63 (14) | 101 (15) | 105 (16) | 269 (15) |
| White blood cells [x 109/L] | 5.1 (3.9, 6.4) | 5.1 (4.0, 6.6) | 5.3 (4.2, 6.6) | 5.2 (4.1, 6.6) |
| Missing | 63 (14) | 79 (12) | 86 (13) | 228 (13) |
| eGFRb [mL/min] | 105 (87, 120) | 108 (96, 121) | 112 (97, 122) | 109 (95, 122) |
| Missing | 59 (13) | 85 (13) | 82 (12) | 226 (13) |
| VACS Index 2.0 | 68 (55, 82) | 60 (51, 75) | 57 (48, 67) | 61 (51, 74) |
| Missing | 229 (51) | 374 (56) | 335 (50) | 938 (53) |
a
Alcohol use categories were based on responses to the Alcohol Use Disorders Identification Test – Consumption questions (AUDIT-C) and standard cut-offs based on current gender: 1) no use (AUDIT-C=0); 2) moderate use (AUDIT-C>0 and <3 for women or AUDIT-C>0 and <4 for men); and 3) unhealthy use (AUDIT-C≥3 for women or AUDIT-C≥4 for men)
b
Median (interquartile range); 2-digit calendar year of enrollment