Table 2.

102-month (8.5-year) restricted mean number of months, and differences in restricted mean months (95% confidence intervals),^a spent in each of the HIV care continuum stages by baseline alcohol use among 1781 antiretroviral therapy-naïve persons who enrolled in the Center for AIDS Clinical Research Network of Integrated Clinical Systems, 2011–2019, and who self-reported on their alcohol consumption within 1 year of enrollment

	Alcohol Use			Difference
HIV care continuum stages	None	Moderateb	Unhealthyb	Moderate – None	Unhealthy – None	Unhealthy – Moderate
In care, not ART initiate	5.1 (4.3, 5.9)	5.4 (4.7, 6.3)	6.6 (5.6, 7.8)	0.3 (−0.8, 1.5)	1.5 (0.1, 2.9)	1.2 (−0.3, 2.6)
Lost to clinic before ART initiation	2.1 (0.8, 3.2)	3.9 (2.6, 5.3)	3.1 (1.8, 4.5)	1.8 (0.0, 3.8)	1.0 (−0.6, 2.8)	−0.8 (−2.7, 0.9)
Dead before ART initiation	0.2 (0.0, 0.7)	c	0.1 (0.0, 0.4)	−0.2 (−0.7, 0.0)	−0.1 (−0.7, 0.4)	0.1 (0.0, 0.4)
In care, not virally suppressed	8.9 (7.3, 10.8)	7.2 (5.9, 8.6)	5.4 (4.4, 6.6)	−1.7 (−4.0, 0.5)	−3.4 (−5.6, −1.6)	−1.8 (−3.5, 0.1)
In care, virally suppressed	62.3 (58.3, 66.1)	61.1 (57.6, 64.2)	59.5 (56.4, 62.7)	−1.2 (−6.0, 3.6)	−2.8 (−7.5, 2.3)	−1.6 (−6.1, 3.0)
Lost to clinic after ART initiation	18.3 (15.2, 21.6)	23.4 (20.6, 26.2)	25.9 (23.3, 28.8)	5.1 (0.8, 9.3)	7.6 (3.1, 11.7)	2.5 (−1.7, 6.9)
Dead after ART initiation	5.1 (3.3, 6.9)	1.1 (0.4, 1.8)	1.3 (0.6, 2.2)	−4.0 (−6.1, −1.9)	−3.8 (−5.7, −1.7)	0.2 (−0.8, 1.4)

^*Abbreviations: ART, antiretroviral therapy

^aDifference estimates may differ slightly from direct subtractions of alcohol use estimates due to rounding

^bModerate alcohol consumption defined as AUDIT-C score >0 and <3 for women and >0 and <4 for men; unhealthy alcohol consumption defined as AUDIT-C score ≥3 for women and ≥4 for men.

^cAmong patients in the Moderate alcohol use group at baseline, there were no deaths prior to ART initiation (no transition to this state).