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. 2023 Jul;33(7):1124–1132. doi: 10.1101/gr.277670.123

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© 2023 Liu et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see https://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 3. — Comparison of alignment methods on partially overlapping DLPFC slices. (A) Vertical subslices were obtained by cropping subslices (blue dotted boxes) from four adjacent slices from DLPFC sample 3, with indicated distances between adjacent slices. Each pair of adjacent subslices overlaps in 70% of their areas. (B) LTARI of pairwise alignments computed by PASTE2, PASTE, Pamona, and Tangram for each pair of adjacent vertical subslices from three samples. (C) Optimal projection of vertical subslices from slice AB of sample 3 onto the same 2D coordinate system using the PASTE2 partial alignment.