Table 1.
Gene |
SNP |
General Population MAFa |
IPF MAF |
IPF Risk |
IPF Mortality Risk |
Reference |
---|---|---|---|---|---|---|
MUC5B | rs35705950 | 0.05 | 0.14–0.31 | Increased | Decreased | 7,9,15 |
TOLLIP | rs5743890 | 0.05 | 0.10 | Decreased | Increased | 7 |
rs5743894 | 0.08 | 0.20 | Increased | 7 | ||
DSP | rs2744371 | 0.23 | 0.14 | Decreased | 21 | |
rs2076295 | 0.43 | 0.46–0.51 | Increased | 8,9,21 | ||
AKAP13 | rs62025270 | 0.11 | 0.25 | Increased | 9 | |
TERT | rs2736100 | 0.48 | 0.43 | Increased | 8 |
MAF is the minor allele frequency from the 1000 Genomes Project