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. Author manuscript; available in PMC: 2023 Sep 28.
Published in final edited form as: Am J Med Sci. 2019 Feb 13;357(5):379–383. doi: 10.1016/j.amjms.2019.02.009

Table 1.

A summary of common SNPs associated with IPF and their effects.


Gene

SNP
General Population
MAFa

IPF MAF

IPF Risk

IPF Mortality Risk

Reference
MUC5B rs35705950 0.05 0.14–0.31 Increased Decreased 7,9,15
TOLLIP rs5743890 0.05 0.10 Decreased Increased 7
rs5743894 0.08 0.20 Increased 7
DSP rs2744371 0.23 0.14 Decreased 21
rs2076295 0.43 0.46–0.51 Increased 8,9,21
AKAP13 rs62025270 0.11 0.25 Increased 9
TERT rs2736100 0.48 0.43 Increased 8
a

MAF is the minor allele frequency from the 1000 Genomes Project