TABLE 1.

LncRNA SNHGs in regulation of osteoarthritis.

LncRNA	miRNA	Targets	Functions	Ref
SNHG1	miR-16–5p	P38 MAPK, NF-κB	Attenuation of osteoarthritis	Lei et al. (2019)
SNHG1	miR-195	IKK-α	Reduces apoptosis and inflammation	Wang et al. (2023a).
SNHG5	miR-26a	SOX2	Increases proliferation of chondrocyte	Shen et al. (2018)
SNHG5	miR-181a-5p	TGFBR3	Blocks IL-1β-induced osteoarthritis	Yue et al. (2021)
SNHG5	miR-10a-5p	H3F3B	Inhibition of apoptosis and promotion of proliferation	Jiang et al. (2021)
SNHG7	miR-34a-5p	SYVN1	Promotes proliferation, inhibits apoptosis and autophagy	Tian et al. (2020)
SNHG7	miR-214–5p	PPARGC1B	Inhibits IL-1β-induced osteoarthritis	Xu et al. (2021)
SNHG9	miR-34a	N/A	Suppresses cell apoptosis	Zhang et al. (2020b)
SNHG12	miR-16–5p	N/A	Induces apoptosis, inflammation, ECM degradation, inhibits proliferation	Yang et al. (2022a)
SNHG14	miR-214–3p	FSTL-1, NLRP3, NF-κB	Inhibits osteoarthritis	Wang et al. (2021a)
SNHG15	miR-141–3p	BCL2L13	Prevents osteoarthritis progression	Zhang et al. (2020c)
SNHG16	miR-373–3p	N/A	Accelerates osteoarthritis occurrence	Fan et al. (2021a)