Table 8. Gene expression fold change (FC) of Ae. aegypti.

Adult Ae. aegypti permethrin-resistant strain
Gene/protein/accession no.	Hotspot	Non-hotspot	T-test
	Gene expression (Fc)		Protein Expression (Fc)
Sodium/potassium-dependent ATPase β2 subunit (Q16RY8)	0.45	3.76	2.96
Enolase phosphatase E1 (Q17Q32)	-2.5	-3.4	-3.18
Glucosidase 2 β (Q16M80)	-2.3	-3.8	-2.88
Troponin I (Q16RS3)	-2.6	-2.0	-2.01
Larvae Ae. aegypti temephos-resistant strain
Gene/protein/accession no.	Hotspot	Non-hotspot	T-test
	Gene expression (Fc)		Protein expression (Fc)
H15 domain containing protein (A0A6I8TV54)	0.54	0.43	2.92
60S ribosomal protein L21 (Q1HRN4)	1.82	2.02	3.05
AAEL01756-PB (J9HFM9)	0.84	2.72	2.31
Tubulin β chain (A0A1S4F2Y4)	-142.9	-10.0	-4.43

Note:—(minus): downregulated proteins.