Table 3. Organization of all confirmed and identified mRNA ligands of hnRNP A2 based on 3′ UTR features.
Pentamer and poly(U) tracts | Poly(U) tracts |
1. Heparin sulfate proteoglycan core protein | 1. SEC61 homolog |
2. KM 102-derived reductase-like factor | 2. Phospholipase c B3 |
3. Cyclooxygenase I | 3. Cathepsin B |
4. Inducible poly(A)-binding protein | 4. Adenylyl cyclase associated protein |
5. GTF2I (transcription factor) | 5. β-actin |
6. CBFB (transcription factor) | 6. Heme oxygenase (decyclin) 1 |
7. Calnexin | 7. γ-actin |
8. Origin recognition complex subunit 5 | 8. Co-β-glucosidase |
9. AAC-11 | 9. Y Box binding protein 1 |
10. Human clone 25077 | |
11. RSU-1/RSP-1 | Ribosomal proteins |
12. KIA0102 | 1. L18a |
13. Unknown clone (accession no. AF009205) | 2. L30 |
14. Phosphatidylinositol synthase | 3. L44 |
4. S18 | |
Nonamer | |
1. KM 102-derived reductase-like factor | Other genes |
2. Unknown clone (accession no. AF009205) | 1. Epithelin 1 and 2 |
2. Cytochrome oxidase subunit II | |
3. Pctaire-1 | |
4. HOXA13 |
Summary of the all of the clones from the two immunoprecipitations that demonstrated EF-67 specific binding. Clones are organized according to the presence or absence or the listed 3′ UTR cis-elements. All of the pentamer containing clones also contain poly(U) tracts, which are defined as a least two tracts with a minimum of five uridines or at least four tracts with a minimum of four uridines.