TABLE 6.

Effect of topical treatment with ACV (0.1%) or MMF (5%), or both, on intracutaneous HSV-1 lesions and mortality in hairless mice

Treatment	MDLAa	MDDa,b	No. of mice with lesions/total no. of mice	Mortality (no. of dead mice/total no. of mice)
Control	5.2 ± 0.4	7.4 ± 0.7	9/9	9/9
5% MMF	6.6 ± 2.0c	9.7 ± 2.6d	9/9c	9/9c
0.1% ACV	5.5 ± 0.5c	8.8 ± 1.5d	8/9c	8/9c
5% MMF + 0.1% ACV	7.0	14	1/9e	1/9e

^aData are mean values for two independent experiments with a total of nine mice for each experimental condition. 

^bMDD, mean day of death. 

^cNot significant. 

^dP < 0.05. 

^eP < 0.001.