Table 2 Clinical outcomes of patients with PE with and without residual DVT.
| PE with DVT (n=320) | PE only (n=99) | HR (95%CI) | P value | |||
|---|---|---|---|---|---|---|
| n (%) | % per patient-year (95%CI) | n (%) | % per patient-year (95%CI) | |||
| Recurrence or aggravation of symptomatic VTE | 14 (4.4) | 2.7 (1.3–4.0) | 3 (3.0) | 1.9 (0.0–4.1) | 1.35 (0.39–4.70) | 0.634 |
| Recurrence or aggravation of symptomatic PE | 9 (2.8) | 1.7 (0.6–2.8) | 3 (3.0) | 1.9 (0.0–4.1) | 0.88 (0.24–3.27) | 0.854 |
| Recurrence or aggravation of symptomatic DVT | 6 (1.9) | 1.1 (0.2–2.0) | 1 (1.0) | 0.6 (0.0–1.9) | 1.75 (0.21–14.50) | 0.601 |
| Acute coronary syndrome | 1 (0.3) | 0.2 (0.0–0.6) | — | — | — | 0.591 |
| Ischemic stroke | 7 (2.2) | 1.3 (0.3–2.3) | 1 (1.0) | 0.6 (0.0–1.9) | 2.15 (0.26–17.45) | 0.464 |
| Death from any cause | 25 (7.8) | 4.6 (2.8–6.5) | 9 (9.1) | 5.6 (2.0–9.3) | 0.82 (0.38–1.76) | 0.614 |
| Death related to VTE | 3 (0.9) | 0.6 (0.0–1.2) | 1 (1.0) | 0.6 (0.0–1.9) | 0.92 (0.10–8.84) | 0.941 |
| Death related to CVD | 4 (1.3) | 0.7 (0.0–1.5) | 1 (1.0) | 0.6 (0.0–1.9) | 1.21 (0.13–10.82) | 0.866 |
| Major bleeding | 9 (2.8) | 2.5 (0.9–4.1) | 2 (2.0) | 2.0 (0.0–4.7) | 1.27 (0.27–5.87) | 0.761 |
| Minor bleeding | 28 (8.8) | 8.1 (5.1–11.1) | 3 (3.0) | 3.0 (0.0–6.4) | 4.09 (0.97–17.19) | 0.037 |
A P value of <0.05 was considered statistically significant. CI: confidence interval; CVD: cardiovascular disease; DVT: deep vein thrombosis; HR: hazard ratio; PE: pulmonary thromboembolism; VTE: venous thromboembolism