Table 1.
Baseline characteristics of patients with myeloid neoplasm in our study cohort.
| All MNs (N = 8,142) |
Monosomy 7 (N = 501) |
Del7q (N = 144) |
P-value -7 vs del7q |
|
|---|---|---|---|---|
| Median age, years | 68 | 69 | 68 | 0.49 |
| Age < 40 year, % | 6.2 | 5.3 | 5.6 | 0.89 |
| Male, % | 54.7 | 58.3 | 68.5 | 0.17 |
| Diagnosis | ||||
| pAML, % | 72 | 65 | 50 | 0.04 |
| MDS, % | 16 | 25 | 35 | 0.02 |
| sAML, % | 6 | 7 | 5 | 0.4 |
| MDS/MPN, % | 5 | 3 | 7 | 0.07 |
| MPN, % | 2 | 1 | 3 | 0.02 |
| History of AA, % | 0.4 | 4 | 2 | 0.24 |
| Cytogenetics | ||||
| normal, % | 53.5 | - | - | - |
| del5/5q, % | 5.4 | 22 | 30.1 | 0.07 |
| isolated -7/7q, % | 1.8 | 20 | 29.4 | 0.03 |
| CK -7/del7q, % | 7.7 | 56.6 | 52.4 | 0.5 |
AA aplastic anemia, CK complex karyotype, MDS myelodysplastic syndrome, MDS/MPN myelodysplastic/myeloproliferative neoplasm, MNs myeloid neoplasms, MPN myeloproliferative neoplasm, pAML primary acute myeloid leukemia, sAML secondary acute myeloid leukemia.