Table 1.
Clinicopathological characteristics of the 144 advanced GBC patients
| Variables | Number (%) or median (range) |
|---|---|
| Age (years) | 63 (36–85) |
| Sex (female) | 95 (65.9%) |
| TB (μmol/L) | 11.8 (4.7–261.6) |
| ALT (IU/L) | 24 (6–842) |
| AST (IU/L) | 25 (13–850) |
| ALB (g/L) | 41.1 (26.4–52.4) |
| CA19-9 (U/mL) | 22.2 (0.1–>1000) |
| CA125 (U/mL) | 19.7 (2.1–1567.0) |
| Extent of liver resection | |
| Wedge resection | 18 (12.5%) |
| Segment IVb and V resection | 84 (58.3%) |
| Right hemihepatectomy | 34 (23.6%) |
| Right trisegmentectomy | 8 (5.6%) |
| Lymph node dissection | |
| D1 | 92 (63.9%) |
| D2 | 52 (36.1%) |
| Extrahepatic bile duct resection | 76 (52.8%) |
| Adjacent organs resection | 15 (10.4%) |
| Portal vein reconstruction | 13 (9.0%) |
| Hepatic artery reconstruction | 16 (11.1%) |
| Estimated blood loss (mL) | 215 (50–800) |
| Tumor stage | |
| T2 | 62 (43.1%) |
| T3 | 57 (39.6%) |
| T4 | 25 (17.3%) |
| LNs metastasis | 121 (84.0%) |
| No. of positive LNs | 3 (0–13) |
| No. of retrieved LNs | 8 (6–18) |
| LNR | 0.33 (0–1) |
| R0 resection | 119 (82.6%) |
| Tumor differentiation | |
| Poorly | 85 (59.0%) |
| Well, moderately | 59 (41.0%) |
| Perineural invasion | 33 (22.9%) |
| Intravascular invasion | 29 (20.1%) |
| Postoperative complications | 48 (33.3%) |
| Postoperative hospital stay (days) | 7 (4–47) |
| Postoperative chemotherapy | 32 (22.2%) |
TB, total bilirubin; ALT, alanine aminotransferase; AST, aspartate transaminase; ALB, albumin; LNs, lymph nodes; LNR, lymph node ratio