Table 3:

Cox regression analyses for determinants of MN recurrence after transplantation*.

Variable	Univariate HR (95% CI)	P value	Multivariate HR [95% CI]	P value
Age at transplantation, per year	1.06 (1.01–1.10)	0.011	1.02 (0.98–1.07)	0.310
Sex
Male	1.00 (ref.)
Female	1.68 (0.48–5.87)	0.418	NS
Hypertension
No	1.00 (ref.)
Yes	5.31 (0.70–40.43)	0.107	NS
Time to kidney failure on native kidneys, per year	0.98 (0.88–1.08)	0.635	NS
Time on dialysis, per month	1.00 (0.98–1.01)	0.604	NS
KT decade
1991–2000	1.00 (ref.)
2001–2010	6.20 (0.68–56.16)	0.105
2011–2020	11.34 (1.29–99.95)	0.029	3.03 (1.02–8.97)	0.046
Preemptive KT
No	1.00 (ref.)
Yes	2.91 (0.81–10.40)	0.100	NS
Type of donor
DBD	1.00 (ref.)
DCD	0.95 (0.20–4.49)	0.944
Living donor	1.51 (0.43–5.33)	0.518
Living related donor	1.07 (0.24–4.78)	0.925	NS
HLA-A/B/DR mismatch
≤3	1.00 (ref.)
>3	1.03 (0.38–2.77)	0.949	NS
HLA-DRB1*03	0.47 (1.61–1.34)	0.157	NS
CIT, per hour	1.01 (0.94–1.08)	0.758	NS
Induction therapy
None	1.00 (ref.)
Basiliximab/Daclizumab	2.28 (0.74–7.01)	0.151
ATG/ALG/ATGAM	0.48 (0.10–2.40)	0.370	NS
Maintenance with CCT + CNI + AMF
No	1.00 (ref.)
Yes	1.90 (0.23–16.01)	0.555	NS
Steroid free/early steroid withdrawal
No	1.00 (ref.)
Yes	0.41 (0.05–3.30)	0.403	NS
DGF
No	1.00 (ref.)
Yes	0.89 (0.32–2.41)	0.818	NS
Rejection episode during follow-up
No	1.00 (ref.)
Yes	1.73 (0.61–4.93)	0.307	NS
eGFR 3 months after KT, per ml/min/1.73 m2	1.00 (0.97–1.02)	0.743	NS
Proteinuria 3 months after KT, per g/24 h	7.55 (2.49–22.86)	<0.001	4.28 (1.47–12.48)	0.008

* Number of events: 18