Figure 3:

Effect of zibotentan, dapagliflozin and the combination on 24-h urinary glucose excretion, food intake and water intake. (A) Effect of 30 mg/kg/day and 100 mg/kg/day zibotentan with or without 3 mg/kg/day dapagliflozin or vehicle on 24-h urinary glucose excretion. (B and C) Twenty-hour water intake and 24-h food intake respectively. For (B) and (C), each point represents mean food intake and water intake per animal with two animals/cage. N = 10–12/group, *P < .05 vs vehicle, ^#P < .05 vs zibotentan mono-treatment groups. Data presented as mean ± SEM.