Fig. 2. A cross-population meta-analysis of UK Biobank and MVP, with loci reaching a nominal threshold of 1 × 10−5 highlighted in green, and the red line indicating genome-wide significance threshold of 5 × 10−8.
TOP: short (≤5 h, n = 62,516) versus normal (7–8 h, n = 412,944) sleep duration, with 28 independent genetic-risk loci reaching genome-wide significance. BOTTOM: long (≥10 h, n = 17,682) versus normal sleep duration with one genome-wide significant locus.