Table 1.
Sample demographics and case/control status
| Populationa | UK Biobank | MVP | |
|---|---|---|---|
| Total N = 493,142 | N | 293,037 | 200,100 |
| Nshort(≤5 h) (%) | 21,086 (7.2) | 41,425 (20.7) | |
| Nmedium(7–8 h) (%) | 264,982 (90.4) | 147,962 (73.9) | |
| Nlong(≥10 h) (%) | 6969 (2.4) | 10,713 (5.4) | |
| European (EUR) N = 445,966 (90.4%) | N (% female) | 278,003 (54.1) | 167,963 (7.4) |
| Age (years) |
Mean (SD): 56.8 (8.0) Median: 58 |
Mean (SD): 66.8 (11.6) Median: 67 |
|
| Sleep duration (hours) |
Mean (SD): 7.3 (1.0) Median: 7 |
Mean: 7.1 (1.3) Median: 7 |
|
| Nshort(≤5 h) (%) | 18,915 (6.8) | 28,139 (16.8) | |
| Nmedium(7–8 h) (%) | 252,567 (90.9) | 130,383 (77.6) | |
| Nlong(≥10 h) (%) | 6521 (2.3) | 9441 (5.6) | |
| African (AFR) N = 27,785 (5.6%) | N (% female) | 5657 (59.0) | 22,128 (13.5) |
| Age (years) |
Mean (SD): 51.86 (8.1) Median: 50 |
Mean (SD): 60.7 (10.9) Median: 61 |
|
| Sleep duration (hours) |
Mean (SD): 6.9 (1.6) Median: 7 |
Mean (SD): 6.4 (1.3) Median: 6 |
|
| Nshort(≤5 h) (%) | 1396 (24.7) | 9956 (45.0) | |
| Nmedium(7–8 h) (%) | 4017 (71.0) | 11,288 (51.0) | |
| Nlong(≥10 h) (%) | 244 (4.3) | 884 (4.0) | |
| Admixed American (AMR) N = 16,250 (3.3%) | N (% female) | 7712 (56.7) | 8538 (9.4) |
| Age (years) |
Mean (SD): 55.4 (8.3) Median: 56 |
Mean (SD): 60.6 (13.2 Median:63 |
|
| Sleep duration (h) |
Mean (SD): 7.2 (1.0) Median: 7 |
Mean (SD):6.7 (1.3) Median:7 |
|
| Nshort(≤5 h) (%) | 628 (8.1) | 2824 (33.1) | |
| Nmedium(7–8 h) (%) | 6928 (89.8) | 5371 (62.9) | |
| Nlong(≥10 h) (%) | 156 (2.0) | 343 (4.0) | |
| East Asian (EAS) N = 3141 (0.6%) | N(% female) | 1670 (67.1) | 1471 (10.8) |
| Age (years) |
Mean (SD): 51.9 (7.8) Median: 51 |
Mean (SD): 59.9 (15.8) Median: 63 |
|
| Sleep duration (h) |
Mean (SD): 7.3 (1.1) Median: 7 |
Mean (SD): 6.5 (1.2) Median: 6 |
|
| Nshort(≤5 h) (%) | 152 (9.1) | 506 (34.4) | |
| Nmedium(7–8 h) (%) | 1470 (88.0) | 920 (62.5) | |
| Nlong(≥10 h) (%) | 48 (2.9) | 45 (3.1) |
aAll groups defined based on reference panel21.