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. 2023 Sep 28;14:6071. doi: 10.1038/s41467-023-41845-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Interfaces between human TSEN34 with the N-terminal extension of TSEN54. TSEN34 is shown as molecular surface. The three claws of TSEN54 are labeled. b Buried surface areas at the interfaces in human TSEN–pre-tRNA complex. c Interfaces between the subunits of human TSEN. Molecular surfaces of TSEN54 and TSEN15, colored in blue and dark orange, respectively. The minimal interface between TSEN54 and TSEN15 is indicated in the black box. The positions of P-loop of TSEN34, the C tail, and the KRKRR motif of TSEN2 are labeled. The N-terminal insertion of TSEN2 is in magenta. d Overlay of the C-terminal domains of TSEN subunits.