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. 2023 Sep 28;13:16352. doi: 10.1038/s41598-023-43449-4

Table 2.

Demographics, clinical characteristics.

Variables VTE group Non-VTE group Odds ratio 95% CI p-value
Number of patients 14 (3.5%) 388 (96.5%)
Male 6 (1.5%) 227 (56.5%) 0.530 0.181–1.563 1.358
Female 8 (1.0%) 161 (40%) 1.880 0.640–5.522 1.358
Age (years) 54.3 (45.1–68.4) 34.4 (23.0–52.5) 1.065 1.029–1.103  < 0.001
BMI (kg/cm2) 28.4 (26.0–29.4) 23.5 (21.3–27.0) 1.129 1.029–1.24 0.001
ISS 13 (8.3–17.5) 9 (9–20) 1.012 0.965–1.061 0.587
Time to surgery (days) 8 (6–10) 7 (5–9) 1.046 0.923–1.185 0.300
Surgery duration (min) 205 (153–219) 168 (129–235) 1.002 0.996–1.008 0.267
Blood loss (ml) 600 (425–737) 300 (100–700) 1.000 0.999–1.001 0.071
Patients with multiple fractures 7 (17.4%) 209 (52.6%) 0.856 0.295–2.295 0.776
Blood transfused (unit)
 PRBC 6 (4.0–11.5) 4 (4.0–10.0) 1.036 0.987–1.087 0.089
 FFP 2 (2.0–7.0) 2 (2.0–6.0) 1.02 0.942–1.104 0.098
Pelvic fracture 6 (1.5%) 212 (52.7%) 0.623 0.212–1.828 0.385
Acetabular fracture 4 (1.0%) 121 (30.1%) 0.883 0.271–2.870 1.000
Both fracture 4 (1.0%) 55 (13.7%) 2.422 0.734–7.993 0.134
d-dimer (ng/ml)
 Pre-op > 10,000 10 (2.5%) 152 (37.8%) 3.882 1.196–12.598 0.016
 Post-op > 10,000 9 (2.2%) 126 (31.3%) 3.743 1.229–11.399 0.013

Continuous variables are presented as median (IQR) and analysed using the Mann–Whitney U test for p-values and using the univariate logistic regression test for odds ratios and 95% CIs. Categorical variables are presented as number (percentage of 402 patients) and analysed with Fisher’s exact or Chi-square test for p-value, odds ratios, and 95% CIs. BMI, body mass index; ISS, injury severity score; PRBC, packed red blood cell; FFP, fresh frozen plasma; CI, confidence interval.