Table 2.

Relationship between clinicopathologic parameters and IAP family members expression in RCC

Characteristics	N	NAIP				BIRC2				BIRC3				XIAP
		Low	High	P		Low	High	P		Low	High	P		Low	High	P
Gender
Male	233	169	64	0.011		116	117	0.454		169	64	0.852		137	96	0.759
Female	109	64	45			59	50			78	31			66	43
Age (year)
≤60	170	119	51	0.460		85	85	0.667		122	48	0.920		103	67	0.645
>60	172	114	58			90	82			125	47			100	72
T stage
T1 + T2	256	167	89	0.048		129	127	0.619		186	70	0.757		153	103	0.791
T3 + T4	86	66	20			46	40			61	25			50	36
N stage
Nx	87	60	27	0.846		42	45	0.532		61	26	0.611		49	38	0.504
N0 + N1	255	173	82			133	122			186	69			154	101
M stage
Mx	77	49	28	0.337		37	40	0.534		58	19	0.490		38	39	0.045
M0 + M1	265	184	81			138	127			189	76			167	102
Pathologic stage
Stage I + II	252	164	88	0.043		127	125	0.632		183	69	0.784		151	101	0.243
Stage III + IV	90	69	21			48	42			64	26			52	46
Histologic grade
grade 1 + 2	213	147	66	0.000		105	108	0.000		163	50	0.000		121	92	0.000
grade 3 + 4	129	86	43			70	59			84	45			82	47
Characteristics	N	BIRC5				BIRC6				BIRC7				BIRC8
		Low	High	P		Low	High	P		Low	High	P		Low	High	P
Gender
Male	233	155	78	0.361		138	95	0.031		212	21	0.415		225	8	0.209
Female	109	67	42			51	58			102	7			102	7
Age (year)
≤60	170	104	66	0.66		89	81	0.000		158	12	0.449		161	9	0.415
>60	172	118	54			100	72			156	16			166	6
T stage
T1 + T2	256	179	77	0.001		143	113	0.000		235	21	0.985		248	8	0.049
T3 + T4	86	43	43			169	40			79	7			79	7
N stage
Nx	87	62	25	0.003		51	36	0.466		77	10	0.193		80	7	0.372
N0 + N1	255	160	95			138	117			237	18			247	8
M stage
Mx	77	60	17	0.007		42	35	0.886		69	8	0.423		69	8	0.003
M0 + M1	265	162	103			147	118			245	20			258	7
Pathologic stage
Stage I + II	252	176	76	0.000		142	110	0.000		231	21	0.000		244	8	0.000
Stage III + IV	90	46	44			47	43			83	7			83	7
Histologic grade
grade 1 + 2	213	155	58	0.000		117	96	0.000		201	12	0.000		205	8	0.000
grade 3 + 4	129	67	62			72	57			113	16			122	7

Bold font indicates significant difference.