TABLE 2.
Vegetation and tissue bacterial counts
| Infecting strain and treatment | No. of rabbits | Bacterial counts (log10 CFU/g) ina:
|
||
|---|---|---|---|---|
| Vegetation | Kidney | Spleen | ||
| SA-1199 | ||||
| Vancomycin | 15 | 5.72 ± 2.33 (1) | 1.72 ± 1.26 (12) | 1.48 ± 0.57 (12) |
| Trovafloxacin | 17 | 4.51 ± 2.38 (5) | 1.67 ± 1.04 (14) | 1.72 ± 1.23 (14) |
| None (control) | 11 | 9.71 ± 0.71 (0) | 5.60 ± 1.53 (0) | 6.34 ± 0.76 (0) |
| MRSA-494 | ||||
| Vancomycin | 15 | 2.01 ± 0.30 (14) | 1.30 ± 0.09 (15) | 1.31 ± 0.08 (14) |
| Trovafloxacin | 17 | 2.35 ± 0.32 (17) | 1.30 ± 0.11 (17) | 1.30 ± 0.07 (17) |
| None (control) | 10 | 8.43 ± 1.16 (0) | 5.65 ± 1.65 (0) | 5.57 ± 0.80 (0) |
a
Values are means ± standard deviations. Values in parentheses are numbers of culture-negative (sterile) specimens.