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. 2023 Sep 12;77:101797. doi: 10.1016/j.molmet.2023.101797

Figure 6.

Figure 6

A. muciniphila suppresses fatty acid absorption via decreasing transporter-related genes in the small intestine. (A) Schematic overview of monocolonization of germ-free mice with A. muciniphila or Bacteroides thetaiotaomicron. (B) Body weight of monocolonized mice (n = 8 per group). (C) Tissue weight (D) OGTT (E) AUC of OGTT (F) qPCR of various nutrient transporter related genes in the jejunum of monocolonized mice (n = 8 per group). ∗P < 0.05, ∗∗P < 0.01, using two-way ANOVA, followed by Bonferroni's multiple comparison test for (C, D), or using ANOVA, followed by Tukey-Kramer post doc for (B, E, F). Data are presented as the mean ± SEM. (G) Representative CD36 images of the jejunum. Scale bars, 100 μm. (H) Heatmap showing saturated or unsaturated fatty acids detected in the plasma of monocolonized mice.