Table 2.
Socio-demographic, treatment trial and delivery data of the three identified clusters
Cluster 1 (n = 133) |
Cluster 2 (n = 51) |
Cluster 3 (n = 103) |
P value |
|
|---|---|---|---|---|
Socio-demographic data | ||||
Sex (male), % (n) |
56.4 (75) |
70.6 (36) |
61.2 (63) |
0.21 |
Age at clozapine initiation (years), mean (sd) |
40.1 (18.6) |
43.0 (14.7) |
46.7 (13.1) |
0.008 |
Time since SSAD diagnosis CDS registration (years), median [IQR] |
6.0 [1.0−16.0] |
11.0 [4.0−20.0] |
17.0 [9.5−24.0] |
<0.001* |
Presence of CMU-c (yes), % (n) |
41.4 (55) |
56.9 (29) |
40.8 (42) |
0.12 |
Hospitalization in psychiatric ward (yes), % (n) |
53.4 (71) |
54.9 (28) |
42.7 (44) |
0.19 |
Duration of hospitalization (days), median [IQR] |
35.0 [12.5–114.0] |
12.0 [4.0–44.0] |
22.0 [3.0–66.0] |
<0.001* |
TT data | ||||
Number of TTs per individual, median [IQR] |
2 [1−3] |
4 [3−5] |
2 [1−3] |
<0.001* |
Duration of TT (days), median [IQR] |
57.0 [29.0−105.8] |
83.5 [34.0−187.3] |
124.5 [57.0−321.5] |
<0.001* |
Individuals with >2 TTs (yes), % (n) |
33.1% (44) |
82.4% (42) |
41.7% (43) |
<0.0001 |
Individuals with at least one TT with APP (yes), % (n) |
51.1 (68) |
90.2 (46) |
68.9 (71) |
<0.0001 |
Prescribers’ data | ||||
Number of prescribers, mean (sd) |
3.1 (1.9) |
4.0 (2.4) |
3.9 (2.2) |
0.003 |
Number of private practitioner prescriber, mean (sd) |
1.2 (1.4) |
1.8 (1.8) |
1.6 (1.5) |
0.02 |
Number of public health system prescribers, mean (sd) |
1.9 (1.1) |
2.2 (1.1) |
2.3 (1.4) |
0.04 |
Legend:
= non-parametrical test (Kruskal–Wallis); APP = antipsychotic polypharmacy, CDS = Chronic Disease Scheme, CMU-c = Couverture maladie universelle complementaire, IQR = interquartile range, min = minimum, max = maximum, SSAD = schizophrenia or schizoaffective disorder, TT = treatment trial. Missing values: time since SSAD CDS registration = 15.7%.