Figure 2.

Comparison of the 2D CON (a) and 2D HN (b) spectra recorded on $\mathit{\alpha }$ -synuclein. The CON ${}^{\mathrm{pro}}$ spectrum (c), shown below the HN panel, clearly illustrates how this experiment provides the missing information with respect to that available in the HN-detected spectrum. In the inset of the 2D CON spectrum, a scheme of a Gly ${}_{i-\mathrm{1}}-{\text{Pro}}_i$ dipeptide highlights the nuclei that give rise to the ${{\mathrm{C}}^{\prime }}_{i-\mathrm{1}}-{\mathrm{N}}_i$ correlations detected in CON spectra (in green).