Table 3.
Association between stroke incidence and risk factor, including FMDa levels, using cox regression analysis.
| Variables | HRb (95%CIc) | P value |
|---|---|---|
| Age | 1.10 (1.02–1.23) | <0.001 |
| Women | 0.91 (0.82–0.94) | 0.003 |
| Current or former smoker | 1.41 (1.27–1.53) | <0.001 |
| Drinker | 1.15 (1.10–1.22) | <0.001 |
| Diabetes | 1.24 (1.15–1.44) | <0.001 |
| Hypertension | 1.35 (1.26–1.52) | <0.001 |
| Dyslipidemia | 1.39 (1.18–1.50) | <0.001 |
| FMD <5.0% | 2.13 (1.48–3.07) | <0.001 |
| FMD as a continuous variable | 1.27 (1.09–1.45) | <0.001 |
| NT-proBNPd > 48 pg/mL | 1.06 (1.02–1.11) | 0.01 |
| hs-cTnTe > 0.014 ng/L | 1.51 (1.23–1.85) | <0.001 |
| eGFRf < 60 mL/min/1.73 m2 | 1.08 (1.03–1.14) | 0.004 |
a
Flow-mediated dilation.
b
Hazard ratio.
c
Confidence interval.
d
N-terminal pro-brain natriuretic peptide.
e
High-sensitivity cardiac troponin T.
f
Estimated glomerular filtration rate.