Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Sep 8;28(5):200. doi: 10.3892/mmr.2023.13087

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 1. — Effect of PA on the NLRP3 inflammasome in MPC5 cells and cell viability assay following dapagliflozin treatment. (A) NLRP3 inflammatory production in MPC5 cells following treatment with different PA concentrations (0, 0.1, 0.2, 0.3 and 0.4 mmol). (B) NLRP3 inflammasome production significantly increased in MPC5 cells treated with 0.2 mmol PA. (C) Cell Counting Kit-8 cytotoxicity assay following treatment with different concentrations of dapagliflozin (2, 5, 10 and 15 µmol). (D) NLRP3 inflammatory protein expression increased in MPC5 cells following treatment with 0.2 mmol PA. **P<0.001, ***P<0.001, ****P<0.0001 vs. control group. PA, palmitic acid; NLRP3, NOD-like receptor thermal protein domain associated protein 3; MPC5, mouse podocyte clone 5; Con, control; dapa, dapagliflozin.