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. 2023 Sep 8;28(5):200. doi: 10.3892/mmr.2023.13087

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effect of dapagliflozin on protein expression and relative mRNA level of NLRP3 and HO-1 in MPC5 cells. (A) Dapagliflozin decreased the protein expression of NLRP3 and increased that of HO-1. (B) Dapagliflozin decreased the relative mRNA expression of NLRP3 and increased that of HO-1. PA, 0.2 mmol; Dapagliflozin, 2 µmol. **P<0.01 vs. control group; ^#P<0.05, ^###P<0.001 vs. PA group. NLRP3, NOD-like receptor thermal protein domain associated protein 3; HO-1, heme oxygenase 1; Dapa, dapagliflozin; MPC5, mouse podocyte clone 5; PA, palmitic acid; Con, control.