Table 3.
The results of the heterogeneity and horizontal pleiotropy tests.
| Behavior exposures | Heart failure GWAS data set | Heterogeneity test (Cochran Q test) | Horizontal pleiotropy test | ||
|---|---|---|---|---|---|
| MR‐Egger regression | IVW model | MR‐Egger intercept | MR‐PRESSO test | ||
| TV screen time | ebi‐a‐GCST009541 | 0.002 | 0.002 | 0.956 | 0.972 |
| finn‐HEARTFAIL | <0.001 | <0.001 | 0.997 | 0.785 | |
| Using a computer | ebi‐a‐GCST009541 | 0.073 | 0.070 | 0.294 | 0.252 |
| finn‐HEARTFAIL | 0.002 | 0.002 | 0.985 | 0.788 | |
| Driving | ebi‐a‐GCST009541 | 0.495 | 0.539 | 0.454 | 0.657 |
| finn‐HEARTFAIL | 0.590 | 0.670 | 0.567 | 0.719 | |
Note: p < .05 was considered as with statistical differences in both heterogeneity test and horizontal pleiotropy test.
Abbreviations: GWAS, genome‐wide association study; IVW, inverse‐variance weighting; MR, Mendelian randomization.