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. 2023 Aug 29;46(9):1082–1089. doi: 10.1002/clc.24101

Table 3.

The results of the heterogeneity and horizontal pleiotropy tests.

Behavior exposures Heart failure GWAS data set Heterogeneity test (Cochran Q test) Horizontal pleiotropy test
MR‐Egger regression IVW model MR‐Egger intercept MR‐PRESSO test
TV screen time ebi‐a‐GCST009541 0.002 0.002 0.956 0.972
finn‐HEARTFAIL <0.001 <0.001 0.997 0.785
Using a computer ebi‐a‐GCST009541 0.073 0.070 0.294 0.252
finn‐HEARTFAIL 0.002 0.002 0.985 0.788
Driving ebi‐a‐GCST009541 0.495 0.539 0.454 0.657
finn‐HEARTFAIL 0.590 0.670 0.567 0.719

Note: p < .05 was considered as with statistical differences in both heterogeneity test and horizontal pleiotropy test.

Abbreviations: GWAS, genome‐wide association study; IVW, inverse‐variance weighting; MR, Mendelian randomization.