Table 3.
The estimated effect of delivery of just-in-time adaptive interventions (JITAIs) on health-related quality of life (HRQOL) scores of caregiver strain, anxiety, and depression by HCT, HD and SCI subgroups, along with 95% CI. The improvements are shown in log-scale, percentage, and original score scale.
| Subgroup and prompt frequency | Beta (95% CI) | Improvement | P values | ||||||
|
|
|
Percentage (95% CI) | Score (95% CI) |
|
|||||
| Caregiver strain | |||||||||
|
|
HCT a | ||||||||
|
|
|
Low (1-2) | –0.03 (–0.13 to 0.08) | –0.02 (–0.12 to 0.08) | –1.20 (–6.01 to 4.13) | .64 | |||
|
|
|
Medium (3-4) | –0.04 (–0.18 to 0.10) | –0.04 (–0.16 to 0.10) | –1.81 (–7.81 to 5.03) | .58 | |||
|
|
|
High (5-6) | –0.07 (–0.24 to 0.10) | –0.07 (–0.21 to –0.11) | –3.24 (–10.33 to 5.13) | .42 | |||
|
|
HD b | ||||||||
|
|
|
Low (1-2) | 0.02 (–0.10 to 0.14) | 0.02 (–0.10 to 0.15) | 1.00 (–5.13 to 7.93) | .76 | |||
|
|
|
Medium (3-4) | –0.00 (–0.15 to 0.14) | –0.00 (–0.14 to 0.15) | –0.05 (–7.05 to 8.06) | .99 | |||
|
|
|
High (5-6) | –0.15 (–0.35 to 0.04) | –0.14 (–0.29 to 0.04) | –7.33 (–15.21 to 2.22) | .12 | |||
|
|
SCI c | ||||||||
|
|
|
Low (1-2) | –0.12 (–0.39 to 0.16) | –0.11 (–0.32 to 0.17) | –5.76 (–16.76 to 8.72) | .40 | |||
|
|
|
Medium (3-4) | –0.17 (–0.33 to –0.00) | –0.16 (–0.28 to –0.00) | –8.05 (–14.67 to –0.19) | .046 | |||
|
|
|
High (5-6) | –0.19 (–0.56 to 0.18) | –0.17 (–0.43 to 0.19) | –9.03 (–22.17 to 9.93) | .31 | |||
| Anxiety | |||||||||
|
|
HCT | ||||||||
|
|
|
Low (1-2) | 0.03 (–0.11 to 0.16) | 0.03 (–0.10 to 0.17) | 1.33 (–4.91 to 8.48) | .69 | |||
|
|
|
Medium (3-4) | –0.02 (–0.18 to 0.14) | –0.02 (–0.16 to 0.14) | –1.01 (–7.92 to 7.03) | .79 | |||
|
|
|
High (5-6) | –0.03 (–0.17 to 0.12) | –0.02 (–0.16 to 0.13) | –1.20 (–7.69 to 6.36) | .74 | |||
|
|
HD | ||||||||
|
|
|
Low (1-2) | 0.04 (–0.13 to 0.20) | 0.04 (–0.12 to 0.22) | 1.91 (–6.38 to 11.66) | .68 | |||
|
|
|
Medium (3-4) | 0.02 (–0.13 to 0.17) | 0.02 (–0.12 to 0.18) | 1.10 (–6.18 to 9.60) | .78 | |||
|
|
|
High (5-6) | –0.12 (–0.32 to 0.08) | –0.11 (–0.27 to 0.09) | –5.70 (–14.06 to 4.52) | .25 | |||
|
|
SCI | ||||||||
|
|
|
Low (1-2) | –0.23 (–0.50 to 0.03) | –0.21 (–0.40 to 0.03) | –10.80 (–20.45 to 1.79) | .09 | |||
|
|
|
Medium (3-4) | –0.30 (–0.45 to –0.14) | –0.26 (–0.36 to –0.13) | –13.30 (–18.8 to –6.91) | <.001 | |||
|
|
|
High (5-6) | –0.28 (–0.62 to 0.06) | –0.24 (–0.46 to 0.07) | –12.60 (–23.97 to 3.39) | .11 | |||
| Depression | |||||||||
|
|
HCT | ||||||||
|
|
|
Low (1-2) | 0.16 (–0.05 to 0.37) | 0.17 (–0.05 to 0.44) | 6.91 (–2.09 to 18.00) | .14 | |||
|
|
|
Medium (3-4) | 0.14 (–0.05 to 0.34) | 0.15 (–0.05 to 0.41) | 6.30 (–2.11 to 16.54) | .15 | |||
|
|
|
High (5-6) | 0.12 (–0.10 to 0.34) | 0.13 (–0.09 to 0.40) | 5.18 (–3.85 to 16.45) | .28 | |||
|
|
HD | ||||||||
|
|
|
Low (1-2) | –0.04 (–0.16 to 0.07) | –0.04 (–0.15 to 0.07) | –2.45 (–8.09 to 3.84) | .43 | |||
|
|
|
Medium (3-4) | –0.04 (–0.14 to 0.07) | –0.04 (–0.13 to 0.07) | –2.07 (–7.41 to 3.81) | .47 | |||
|
|
|
High (5-6) | –0.17 (–0.33 to –0.01) | –0.16 (–0.28 to –0.01) | –8.79 (–15.69 to –0.70) | .03 | |||
|
|
SCI | ||||||||
|
|
|
Low (1-2) | –0.06 (–0.31 to 0.19) | –0.06 (–0.27 to 0.21) | –3.05 (–13.46 to 10.37) | .63 | |||
|
|
|
Medium (3-4) | –0.13 (–0.27 to 0.02) | –0.12 (–0.24 to 0.02) | –5.95 (–11.87 to 0.83) | .08 | |||
|
|
|
High (5-6) | –0.10 (–0.40 to 0.19) | –0.10 (–0.33 to 0.21) | –4.88 (–16.43 to 10.63) | .50 | |||
aHCT: hematopoietic cell transplantation.
bHD: Huntington disease.
cSCI: spinal cord injury.