TABLE 2.
Distribution of detected pathogens in bile samples of patients with PSC
| PSC cohort n = 114, n (%) | |
|---|---|
| Median no. bacterial/fungal isolates per patients (range) | 1 (0–6) |
| No. patients with positive cultures | 87 (76) |
| Enterobacteriaceae a | 28 (25) |
| Enterococcus spp.b | 42 (37) |
| Candida spp.c | 22 (19) |
| Other Streptococcus spp. and/or Staphylococcus spp.)d | 31 (27) |
| Other Streptococcus spp. | 25 (22) |
| Staphylococcus spp. | 10 (9) |
| Only 1 pathogen isolated | 42 (37) |
| Multiple (≥2) pathogens isolated | 45 (40) |
Note: Data are n (%) of patients, unless indicated otherwise. Primary sclerosing cholangitis (PSC); species (spp.).
Enterobacteriaceae include Escherichia coli, Klebsiella spp, Enterobacter spp., and Citrobacter spp.
Enterococcus spp. include Enterococcus faecalis, Enterococcus faecium, Enterococcus gallinarum, and Enterococcus casseliflacus.
Candida spp. include Candida albicans, Candida dubliniensis, Candida tropicalis, Candida krusei, Candida kefyr, and Candida glabrata.
Other Streptococcus and/or Staphylococcus include Staphylococcus haemolyticus, Staphylococcus aureus, Staphylococcus lentus, Staphylococcus epidermidis, Streptococcus parasanguinis, Sreptococcus salivinarius, Streptococcus sanguinis, Streptococcus mitis, Streptococcus oralis, Streptococcus cristatus, and Streptococcus anginosus.