TABLE 4.
Modal MICs of amphotericin B and itraconazole for nine mold isolates used in animal challenges and interpretive summary of the effects of these agents against experimental infectionsa
| Results for amphotericin B
|
Results for itraconazole
|
||||
|---|---|---|---|---|---|
| Fungus isolate | MIC (μg/ml) | Response | Fungus isolate | MIC (μg/ml) | Response |
| R. arrhizus 26 | 0.25 | Active | A. fumigatus 10 | 0.25 | Active |
| R. arrhizus 27 | 0.25 | Active | A. flavus 01 | 0.5 | Active |
| A. flavus 01 | 1 | Not active | P. boydii 24 | 1 | Not active |
| A. fumigatus 10 | 1 | Active | P. boydii 25 | 1 | Not active |
| F. solani 16 | 1 | Not active | R. arrhizus 26 | 2 | Not active |
| F. oxysporum 15 | 2 | Not active | F. oxysporum 15 | >16 | Not active |
| F. oxysporum 15a | 2 | ?b | F. oxysporum 15a | >16 | ?b |
| P. boydii 24 | 4 | Not active | F. solani 16 | >16 | Not active |
| P. boydii 25 | 4 | Not active | R. arrhizus 27 | >16 | Not active |
a
Results for the two compounds are listed separately, ranked in increasing order of MIC.
b
Results are too inconclusive for interpretation.