Table 1.
Demographic, clinical, mycological, and antifungal treatment data of seven patients diagnosed with sporotrichosis in ocular adnexa from January to December 2018 in Paraíba, Northeast Brazil
| Patient ID | Sex/age (years) | Occupation | Exposure | Mycological examination | PCR identification | Type of lesion | Treatment and dosage | Treatment (months) |
|---|---|---|---|---|---|---|---|---|
| Patient 1 | F/15 | Student | Contact with cat without injury | Sporothrix sp. | Sporothrix brasiliensis | Nodulation in the lower eyelid and tarsal conjunctiva of the right eye with granulomatous appearance | ITZ 200 mg/day (2 cap/day)* | 3 |
| Patient 2 | M/13 | Student | Contact with exudate from a cat skin lesion without injury | Sporothrix sp. | S. brasiliensis | Lesion in the tarsal conjunctiva of the right eye | ITZ 100 mg/day (1 cap/day) | 3 |
| Patient 3 | F/28 | Housewife | Contact with cat wounds without injury | Sporothrix sp. | S. brasiliensis | Lesion on the left hand accompanied by subcutaneous nodules on the left forearm + lesion in the tarsal and bulbar conjunctiva of the right eye and nodular lesion in upper eyelid | ITZ 200 mg/day (2 cap/day) | 3 |
| Patient 4 | M/24 | Public service worker | Scratching by cat on left forearm | Sporothrix sp. | Not performed | Ulcer and painful lymphatic nodules on the left forearm + submandibular and left cervical lymphadenopathy + nodule in the region of the lachrymal gland, painful on palpation, and inflammation + arthralgias | ITZ 400 mg/day (4 cap/day)† | 3 |
| Patient 5 | F/8 | Student | Cat without injury | Sporothrix sp. | Not performed | Hyperemia and granulomas in the superior and inferior tarsal conjunctiva + preauricular adenomegaly | Concentrated potassium iodide solution (1 g/mL), 2.25 g/day | 3 |
| Patient 6 | F/50 | Housewife | Cat without injury | Sporothrix sp. | Not performed | Hyperemia with tarsal conjunctival secretion and granuloma in the lower eyelid | ITZ 200 mg/day (2 cap/day) | 6 |
| Patient 7 | F/27 | Unemployed | Without contact with animals or trauma | Sporothrix sp. | Not performed | Granulomatous lesion in the lower eyelid of the right eye + pre-auricular and cervical lymphadenomegaly | ITZ 200 mg/day (2 cap/day)‡ | 4 |
ITZ = itraconazole; PCR = polymerase chain reaction.
*
Daily.
†
Reduced to 200 mg/day in the first visit at the infectious disease outpatient clinic.
‡
Reduced to 100 mg/day after 10 weeks.