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. 2023 Sep 7;123(18):11137–11189. doi: 10.1021/acs.chemrev.3c00335

Table 2. Summary of Representative Architected Flexible Devices Prepared through Mechanically-Guided 3D Assembly Methods.

Applications Devices Assembly methods Device forms Structure-induced functionalities Superiorities comparing to planar counterparts Reference
Cell devices Inter/intracellular recorders Buckling 3D arc-shaped Vertically directed sensing diodes with predesigned locations High density measurements of transmembrane potential at multiple locations (325)
  Single cell microgrippers Folding Polyhedral Conformal cell capture enabled by folded gripper arms Nondestructive and real-time analysis of 3D surface of cell (184, 372)
Organoid devices 3D electronic frameworks Buckling Conformally wrapping Compliant 3D electronic neural interface in conformal geometries 3D spatiotemporal mapping of spontaneous neural activities (127)
  Shell microelectrode arrays Folding Polyhedral 3D conformal shells with tunable contact area between electrode and target 3D spatiotemporal recording of encapsulated organoids with large contact area (128)
Electronic tissue scaffolds Spherical cap-shaped electronic cell scaffold Buckling Hemispherical Creation of biomimetic 3D microenvironments Noninvasive real-time investigations of cell activities (138)
  Tubular scaffolds Rolling Tubular Biomimetic tubular structures with multilayer walls Enhanced viability and precise multicellular layering of artificial arteries (375)
In situ monitoring devices Piezoelectric microsystems Buckling 3D arc-shaped 3D compliant thin piezoelectric structure with high sensitivity to external forces Enhanced signals with high reproducibility for differentiating various motion states (132)
  Climbing-inspired twining electrodes Rolling 3D helical Twining electrode capable of self-climbing along nerves Conformal neural interface for electrical stimulation and recording (310)
  3D multifunctional membranes Curving Conformal curvilinear 3D conformal electronic membranes Epicardial mapping and stimulation with a mechanically stable interface during normal cardiac cycles (191)
In situ therapeutic devices “Hookworms” microgrippers Folding Worms-mouthparts-shaped Foldable sharp microtips that ensure effective latching onto the GI mucosa Enhanced drug delivery performances enabled by controlled long-term residency (134)
  Pain-blocking microfluidic devices Rolling 3D helical Soft, curled, nerve-clasping microfluidic channels with secure sutureless attachment to nerves Long-term in situ pain relief through neural cooling (388)
Surgical instruments Instrumented catheter Curving Complex curvilinear 3D conformal electronic interfaces High-density spatiotemporal mappings of multiple biological signals and surgical operations (135, 158)
3D electromagnetic devices Hemispherical/spherical ESAs Buckling Hemispherical High volume occupation of the Chu-sphere Wireless communication with enhanced Q factors and broadened working angles (301, 404)
  3D magnetically charged particle optics Rolling Tubular Self-rolling tubular microsized electromagnets Fast beam manipulation (405)
  Cubic magnetic sensors Folding Polyhedral Spatial rearrangement of sensing elements through self-folding Simultaneous measurements of three magnetic field components in 3D space (98)
3D displays Foldable quantum dot light-emitting Folding Polyhedral 3D foldable QLEDs in origami forms enabled by customized creases 3D reconfigurable displays (297)
  Ultrathin inorganic light-emitting diodes Curving Complex curvilinear 3D arrangement of multilayer LED arrays 3D multilayer displays that can be integrated on various unusual substrates (45)
3D devices for photodetection and Light manipulation 3D photodetectors Buckling Hemispherical Spatial arrangement of photodetectors Simultaneous measurements of the direction, intensity and angular divergence of incident light (217)
  Nano-kirigami metasurface Folding Kirigami Out-of-plane configurations of plasmonic materials Giant intrinsic optical chirality (246)
Eyeball cameras Compound eyes cameras Curving Hemispherical Bioinspired spatial arrangements of optical elements on hemispherical surfaces Wide field of view, low levels of chromatic aberrations and deep depth of field (129)
  Aquatic eyeball cameras Curving Hemispherical     (426, 427)
  Tunable hemispherical electronic eye camera Curving Hemispherical Tunable ultrathin kirigami membranes consisting of optoelectronic pixels Imaging of objects at different distances with low aberration (130)
Microbatteries Spiral microbatteries and microelectrodes Rolling Tubular 3D stacking of electrode materials High loadings of electrode materials with reduced footprint area (313, 314)
Energy harvesters Piezoelectric element 3D structures Buckling 3D arc-shaped 3D compliant piezoelectric structure with multiple vibration modes High power output under wide range of frequencies (132)
  3D flexible thermoelectric helical array Buckling 3D helical Enlarged temperature gradients through creations of altitude intercept Enhanced heat exchange efficiency and output power (289)
Robotics Electronic fliers Buckling Shapes resembling wind-dispersed seeds Rotational falling and low terminal velocities Flying with controlled rotational kinematics and enhanced stability (22)
  Aquatic robots Rolling Tubular Construction of tubular jet propulsion engines Untethered multimodal swimming in a controlled manner (15)
  Wall-climbing robot Buckling 3D arc-shaped Reconfigurable 3D structures capable of large deformations Multiple locomotion modes (16)