Table 1.
Comparing TPR at Different FPR Cutoffs Using logBF2 to Distinguish Target-Specific Accelerated Loci From Nontarget-Specific Accelerated Loci Under Different Scenarios of Target Mis-specification Between PhyloAcc-GT and PhyloAcc.
| Testing | Method | TPR | TPR |
|---|---|---|---|
| Scenario | @1%FPR | @5%FPR | |
| 1 | PhyloAcc-GT | 0.89 | 0.96 |
| PhyloAcc | 0.76 | 0.84 | |
| 2 | PhyloAcc-GT | 0.99 | 1 |
| PhyloAcc | 0.92 | 1 | |
| 3 | PhyloAcc-GT | 0.97 | 0.98 |
| PhyloAcc | 0.94 | 0.97 |
Note.—Species that are truly in the accelerated state either overlap (rows 1 & 2), include (rows 3 & 4) or are completely different from input target species (rows 5 & 6).