TABLE 5.
Fungicidal activities of triazoles and AMB against filamentous fungi other than Aspergillus spp.
| Organism | Drug | MIC (μg/ml) | MFC99 (μg/ml) | MFC95 (μg/ml) | MFC90 (μg/ml) |
|---|---|---|---|---|---|
| Trichophyton rubrumA26761 | BMS | 0.13 | >16 | >16 | >16 |
| FLU | 2 | >128 | >128 | >128 | |
| ITR | 0.25 | >16 | >16 | >16 | |
| AMB | 0.5 | 0.25 | |||
| Trichophyton mentagrophytesA27979 | BMS | 0.03 | >2 | >2 | >2 |
| FLU | 2 | >128 | >128 | >128 | |
| ITR | 0.06 | >2 | >2 | >2 | |
| Microsporum gypseumA26835 | BMS | 0.13 | >2 | >2 | >2 |
| FLU | 128 | >128 | >128 | >128 | |
| ITR | 0.5 | >2 | >2 | >2 | |
| Epidermophyton floccosumA26765 | BMS | 0.03 | >2 | 1 | 1 |
| FLU | 4 | >128 | >128 | >128 | |
| ITR | 0.06 | 0.5 | 0.5 | 0.5 | |
| Curvularia sp. strain SC8156 | BMS | 2 | 16 | 8 | 8 |
| FLU | 8 | >128 | >128 | >128 | |
| ITR | 0.5 | >16 | 4 | 4 | |
| AMB | 0.5 | 32 | 16 | 16 | |
| Curvularia sp. strain SC2475 | BMS | 1 | >16 | >16 | >16 |
| FLU | 32 | 64 | |||
| ITR | 0.25 | 8 | 4 | 4 | |
| AMB | 0.13 | 4 | 1 | 1 | |
| Cladosporium carrionii ATCC 22864 | BMS | 0.13 | >16 | >16 | >16 |
| FLU | 8 | >128 | >128 | >128 | |
| ITR | 0.13 | >16 | >16 | >16 | |
| AMB | 4 | >32 | >32 | 4 | |
| Fonsecaea pedrosiA26042 | BMS | 0.13 | >16 | >16 | >16 |
| FLU | 64 | >128 | |||
| ITR | 0.13 | >32 | 32 | 8 | |
| AMB | 4 | >16 | >16 | >16 | |
| Phialophora verrucosa ATCC 4806 | BMS | 0.06 | 4 | 4 | 4 |
| FLU | 32 | >128 | |||
| ITR | 0.06 | 0.5 | 0.5 | 0.5 | |
| AMB | 2 | 4 | |||
| Pseudallescheria boydiiA25933 | BMS | >16 | >16 | >16 | >16 |
| FLU | >128 | >128 | >128 | >128 | |
| ITR | >16 | >16 | >16 | >16 | |
| AMB | 8 | >32 | >32 | >32 | |
| Sporothrix schenckiiA25976 | BMS | 1 | >16 | >16 | >16 |
| FLU | >128 | >128 | |||
| ITR | 0.5 | >16 | >16 | >16 | |
| AMB | 1 | 1 |