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. 2023 Jul;23(4):403–408. doi: 10.7861/clinmed.2022-0556

Table 1.

Basic characteristics of local patients with HDV diagnosed between July 2009 and December 2021

Parameters (n=61) Number of patients, n (%)
Mean age in years, (range) 44.8 (23–76)
Sex
Male 26 (42%)
Female 35 (58%)
Ethnicity
Asian 13 (21%)
Black 8 (13%)
Mixed 9 (15%)
White 13 (21%)
Unknown 18 (30%)
Virology
HBS Ag 61 (100%)
HBeAg +ve 14 (23%)
HBeAg –ve 47 (77%)
Hep e Ag Ab +ve 46 (75%)
Hep e Ag Ab –ve 15 (25%)
HBV core Ab +ve 59 (89%)
HCV Ab +ve 2 (3%)
HIV Ag/Ab 0 (0%)
HDV virology
HDV IgG Ab 61 (100%)
HDV RNA +ve 22 (36%)
Staging of liver disease
Cirrhosis on imaging 30 (49%)
Mean transient elastography at diagnosis in kPa (range) 6.44 (2.7–23.2)
Chronic HBV therapy
Tenofovir 20 (33%)
Entecavir 14 (23%)
Lamivudine 7 (12%)
HDV-specific therapy
IFN-α 17 (28%) received treatment; 13 (21%) did not continue because of adverse effects
Liver transplantation 13 (21%)
Death 3 (5%)
Blood tests at diagnosis Mean value (range)
AST (U/L) 54.64 (14–199)
ALT (U/L) 98.18 (9–2236)
ALP (U/L) 72 (28–201)
Bilirubin (μmol/L) 18.93 (2–319)
Albumin (g/L) 43 (23–56)
Sodium (mmol/L) 140.26 (128–146)
Creatinine (mmol/L) 68.95 (36–164)
INR 1.18 (0.9–3.7)
Hb (g/L) 131.63 (79–169)
MCV (fL) 86.2 (65–103.1)
Neutrophils (109/L) 2.82 (0.4–7.7)
Lymphocytes count (109/L) 1.53 (0.4–3.3)
Total white cell count (109/L) 4.84 (1.7–11.2)
Platelet count (109/L) 157.1 (29–383)

Ab = antibody; Ag = antigen; ALP= alkaline phosphatase; ALT = alanine transaminase; AST = aspartate transaminase; HCV = hepatitis C virus; HDV = hepatitis D virus; HB = hepatitis B virus; IFN = inteferon; INR = international normalised ratio.