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(A) Representative echocardiographic images of the long-axis view of hearts. (B) Quantification LA areas in WT and Nlrp3–/– mice that were subjected to sham or CKD procedures. (C) SBP measurement. (D) Representative pulsed-wave Doppler images. (E) Quantification of E/A ratios. Data are expressed as the mean ± SEM. *P < 0.05 and ***P < 0.001, by ordinary 1-way ANOVA with Šidák’s multiple-comparison test (B and C).
