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. 2023 Sep 15;11:1197607. doi: 10.3389/fped.2023.1197607

Table 2.

Duration of respiratory support and length of hospitalization in NICU.

Variables (days, mean ± SD) Classical method (n = 2,181) InSurE method (n = 295) LISA method (n = 191) p-value Pairwise comparisons
InSurE-LISA InSurE-Classical LISA-Classical
Duration of invasive ventilator support 22.36 ± 29.94 3.99 ± 11.93 8.78 ± 29.32 <0.001* 0.014* <0.001* <0.001*
Duration of noninvasive ventilator support 26.44 ± 24.41 24.78 ± 19.72 26.95 ± 20.63 0.271
Duration of oxygen supply 6.74 ± 11.97 2.97 ± 8.83 5.98 ± 11.70 <0.001* 0.083 <0.001* 0.104
Duration of high flow nasal cannula 15.31 ± 16.84 13.67 ± 14.03 13.20 ± 13.66 0.768
Length of hospitalization 79.68 ± 48.87 64.91 ± 24.07 75.91 ± 36.80 <0.001* 0.005* <0.001* 0.379

SD, standard deviation; InSurE, Intubation-Surfactant-Extubation; LISA, less invasive surfactant administration.

*

p-value < 0.05.