Table 1.
Baseline characteristics and risk factors of the high-risk group in the derivation cohort.
| Characteristics | Total | LR | HR | p-value |
|---|---|---|---|---|
| Total, n (%) | 1,728 (100) | 1,613 (93.3) | 115 (6.7) | |
| Age, median [IQR] | 46.00 [38.00, 52.00] | 46.00 [38.00, 52.00] | 39.00 [32.00, 47.50] | <0.001 |
| Gender, n (%) | <0.001 | |||
| Male Female |
303 (17.5) 1,425 (82.5) |
253 (15.7) 1,360 (84.3) |
50 (43.5) 65 (56.5) |
|
| LTD, median [IQR] | 0.50 [0.40, 0.70] | 0.50 [0.40, 0.70] | 0.70 [0.55, 0.80] | <0.001 |
| Tumor location, n (%) | 0.044 | |||
| Upper Middle Lower Isthmus |
422 (24.4) 622 (36.0) 615 (35.6) 69 (4.0) |
406 (25.2) 571 (35.4) 572 (35.5) 64 (4.0) |
16 (13.9) 51 (44.3) 43 (37.4) 5 (4.3) |
|
| Echogenicity, n (%) | 1.000 | |||
| Nonhypoechoic Hypoechoic |
29 (1.7) 1,699 (98.3) |
27 (1.7) 1,586 (98.3) |
2 (1.7) 113 (98.3) |
|
| Boundary, n (%) | 0.728 | |||
| Not clear Clear |
1,633 (94.5) 95 (5.5) |
90 (5.6) 1,523 (94.4) |
5 (4.3) 110 (95.7) |
|
| Shape, n (%) | 0.804 | |||
| Not regular Regular |
1,581 (91.5) 147 (8.5) |
1,477 (91.6) 136 (8.4) |
104 (90.4) 11 (9.6) |
|
| Aspect ratio, n (%) | 0.129 | |||
| ≤1 >1 |
630 (36.5) 1,098 (63.5) |
580 (36.0) 1,033 (64.0) |
50 (43.5) 65 (56.5) |
|
| Calcification, n (%) | <0.001 | |||
| No Micro Macro Both |
883 (51.1) 731 (42.3) 99 (5.7) 15 (0.9) |
849 (52.6) 658 (40.8) 93 (5.8) 13 (0.8) |
34 (29.6) 73 (63.5) 6 (5.2) 2 (1.7) |
|
| CDFI, n (%) | 0.022 | |||
| No Rare Abundant |
850 (49.2) 573 (33.2) 305 (17.7) |
807 (50.0) 523 (32.4) 283 (17.5) |
43 (37.4) 50 (43.5) 22 (19.1) |
|
| Multifocality, n (%) | 0.011 | |||
| No Yes |
1,128 (65.3) 600 (34.7) |
1,066 (66.1) 547 (33.9) |
62 (53.9) 53 (46.1) |
|
| Bilateral, n (%) | 0.010 | |||
| No Yes |
1,280 (74.1) 448 (25.9) |
1,207 (74.8) 406 (25.2) |
73 (63.5) 42 (36.5) |
|
| HT, n (%) | 0.239 | |||
| No Yes |
1,169 (67.7) 559 (32.3) |
1,085 (67.3) 528 (32.7) |
84 (73.0) 31 (27.0) |
LR, low risk; MHR, medium-high risk; LTD, largest tumor diameter; HT, Hashimoto’s thyroiditis.