TABLE 1.
Results of two-compartment modeling of the effect of indinavir on viral productiona
| Statistical parameter | Indinavir-induced downturn in viral generation (log10) | Viral generation half-life (days) |
|---|---|---|
| Mean | 2.56 | 3.0 |
| SD | 1.34 | 1.7 |
| Median | 2.71 | 2.5 |
| Range | −0.42–4.7 | 1.4–6.4 |
Based on two-compartment modeling of 14 subjects performed by using simultaneous inhomogenous differential equations. Half-lifes were calculated by using the rate constants generated from the solution of the equations and the standard formula for half-life.