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. 1998 Feb;42(2):358–361. doi: 10.1128/aac.42.2.358

TABLE 1.

Results of two-compartment modeling of the effect of indinavir on viral productiona

Statistical parameter Indinavir-induced downturn in viral generation (log10) Viral generation half-life (days)
Mean 2.56 3.0
SD 1.34 1.7
Median 2.71 2.5
Range −0.42–4.7 1.4–6.4
a

Based on two-compartment modeling of 14 subjects performed by using simultaneous inhomogenous differential equations. Half-lifes were calculated by using the rate constants generated from the solution of the equations and the standard formula for half-life.