. 2023 Sep 30;14(9):644. doi: 10.1038/s41419-023-06165-5

Table 3.

Mutation detected in proteins from proteomic data obtained by spatially resolved proteomic using XMAn database.

Found in samples	Patients^a Number	Protein	Mutation	Cancers
p53 signature	2	Histone H4	c.239A>Gp.K80R\|AKRRTVT\|Missense	Endometrium
p53 signature	2	Histone H2B type 1-C/E/F/G/I	c.181G>T p.G61C\|KAMCIMN\|Missense	Endometrium
STIL	3	60 S ribosomal protein L14	p.A159_K160insAA\|AAAAAKVP\|Insertion - in frame	Endometrium, Ovary, Breast
STIC	2	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	c.767C>A p.P256H\|GPLHVPF\|Missense\|	Large intestine
Normal-p53 signature	2/2	Hemoglobin subunit delta	c.427G>T p.A143S\|NALSHKY\|Missense	Lung
	2/2	Histone H2B type 1-C/E/F/G/I	c.133G>C p.V45L\|VYKLLKQ\|Missense	Breast
	2/2/1 HGSC	Actin, alpha cardiac muscle 1	c.166G>A p.V56I\|DSYIGDE\|Missense	Endometrium
	1/3	Synaptic vesicle membrane protein VAT-1 homolog	c.278T>G p.L93R\|FADRMAR\|Missense	Lung
	3/3	Isoform 2 of Drebrin-like protein	c.746G>A p.R249Q\|SRNQNEQ\|Missense	Endometrium
	2/3/1 STIL	Isoform 2 of Synaptopodin-2	c.3392C>T p.P1131L\|RPTLWEA\|Missense	Skin
	2/2/1 STIL	polyubiquitin c	c.368G>C p.G123A\|IFAAKQL\|Missense	Breast
p53signature/STIL	2/3	Isoform 2 of Tropomyosin beta chain	c.835C>A p.L279M\|QTLMELN\|Missense	Autonomic ganglia
Normal-p53/STIL	2/3/2:1 STIC	Histone H1.4	c.262G>T p.V88L\|KSLLSKG\|Missense	Esophagus
Nomal-p53/STIL/STIC	1/3/3/2/1 HGSC	Vimentin	c.1313C>G p.S438^a\|DTH\|Nonsense	Endometrium
	4/4/3/2	Laminin subunit gamma-1	c.2033C>T p.P678L\|SARLGPG\|Missense	Breast
	4/4/4/4: HGSC	Histone H3.1	c.368A>G p.K123R\|IMPRDIQ\|Missense	Endometrium

^aOnly mutations found in more than two patients.