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. 2022 Dec 15;122(18):3600–3610. doi: 10.1016/j.bpj.2022.12.018

Figure 3.

Figure 3

FL2 knockdown results in increased focal adhesion turnover at the leading edge. (A–D) (A and C) Representative immunofluorescence images of U2OS cells along a scratch stained for (A) FAK or (C) p-FAK. Red lines indicate 5.6-μm-wide region of leading edge analyzed in (B and D). (B and D) Scatterplots of fluorescence intensity of (B) FAK and (D) p-FAK. Data points represent individual FAs. (B: n = 2569,3057; D: n = 1458,1426, mean ± SEM; Welch’s t-test, ∗p < 0.05, ∗∗∗∗p < 0.0001). To see this figure in color, go online.