Fig. 3.

Forest plot (unweighted) of the area under the curve (AUC) and 95% confidence intervals (CI) of included studies assessing models that included FIT as a variable, subgroup is by outcome aimed to predict. Where models were validated, these scores are used in the forest plot. $denotes the model used gFOBT, not FIT. ˆdenotes a development and validation model; ∗denotes a validation only model. If no denotation, the model was development only. Studies that do not have confidence intervals did not report dispersion data. Widlak 2018a for CRC combined FIT and FC; Widlak 2018b for CRC combined FIT and volatile organic compounds. Abbreviations: AUC = Area Under the Curve; CI = Confidence Interval; CRC = Colorectal Cancer; ACN = Advanced Colorectal Neoplasia; AA = Advanced Adenoma; HGD = High Grade Dysplasia; HRA = High Risk Adenoma.