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Rho activation causes eversion in tumor epithelial acini. (A) Images of acini assembled by 344SQ tumor epithelial cells assembled in 3D Matrigel culture stained for F-actin or DNA. (B) Time-lapse images of a single acinus assembled by 344SQ cells, treated with Rho activator II (1 μg/mL) at 0 h (see Video 12). Scale bar, 50 μm.
