Table 1.
Detailed information on the GWAS datasets used in this MR study.
| Dataset type | Item | GWAS ID | Author | Consortium | Year | Population | Sample size | Sex |
|---|---|---|---|---|---|---|---|---|
| Exposure | Mood instability | ukb-b-14,180 | Ben Elsworth | MRC-IEU | 2018 | European | 451,619. 204,412 cases and 247,207 controls | Males and females |
| Body mass index | ukb-b-19,953 | Ben Elsworth | MRC-IEU | 2018 | European | 461,460 | Males and females | |
| Current tobacco smoking | ukb-b-223 | Ben Elsworth | MRC-IEU | 2018 | European | 462,434 | Males and females | |
| Alcohol intake frequency | ukb-b-5779 | Ben Elsworth | MRC-IEU | 2018 | European | 462,346 | Males and females | |
| Total body bone mineral density | ebi-a-GCST005348 | Medina-Gomez C | NA | 2018 | European | 56,284 | Males and females | |
| Heavy physical activity | ukb-b-13,184 | Ben Elsworth | MRC-IEU | 2018 | European | 460,376. 197,006 cases and 263,370 controls | Males and females | |
| Outcome | Low back pain | finn-b-M13_LOWBACKPAIN | NA | FinnGen | 2021 | European | 13,178 cases and 164,682 controls | Males and females |
| Low back pain | NA | Bjornsdottir G | NA | 2022 | European | 119,100 cases and 909,847 controls | Males and females |