Table 1.
Outcome Variable | Levels of Postnatal Maternal Care | Prenatal Bisphenol Treatment Group | Effect relative to Corn Oil +/− SEM | t-value | p-value* |
---|---|---|---|---|---|
Percent Eyes Open at PND 15 (Total Pups) | Low Licking/Grooming (16th percentile) | 50 μg/kg BPA | −40.2951 +/− 21.9672 | −1.8343 | 0.0747 |
50 μg/kg Mixed BP | −50.3822 +/− 18.3301 | −2.7486 | 0.0092 | ||
150 μg/kg Mixed BP | −43.5898 +/− 17.8518 | −2.4418 | 0.0195 | ||
Mid Licking/Grooming (50th percentile) | 50 μg/kg BPA | −10.8450 +/− 13.3596 | −0.8118 | 0.4221 | |
50 μg/kg Mixed BP | −22.9496 +/− 12.5157 | −1.8337 | 0.0748 | ||
150 μg/kg Mixed BP | −11.6094 +/− 12.3743 | −0.9382 | 0.3542 | ||
High Licking/Grooming (84th percentile) | 50 μg/kg BPA | 19.0713 +/− 17.0289 | 1.1199 | 0.2700 | |
50 μg/kg Mixed BP | 4.9173 +/− 17.3990 | 0.2826 | 0.7790 | ||
150 μg/kg Mixed BP | 20.8772 +/− 17.5671 | 1.8840 | 0.2422 | ||
Percent Eyes Open at PND 15 (Males) | Low Licking/Grooming (16th percentile) | 50 μg/kg BPA | −37.9521 +/− 22.3507 | −1.6980 | 0.0979 |
50 μg/kg Mixed BP | −63.9907 +/− 18.6500 | −3.4311 | 0.0015 | ||
150 μg/kg Mixed BP | −46.6656 +/− 18.1634 | −2.5692 | 0.0144 | ||
Mid Licking/Grooming (50th percentile) | 50 μg/kg BPA | −10.9718 +/− 13.5928 | −0.8072 | 0.4247 | |
50 μg/kg Mixed BP | −29.1892 +/− 12.7342 | −2.2922 | 0.0277 | ||
150 μg/kg Mixed BP | −16.5370 +/− 12.5903 | −1.3135 | 0.1971 | ||
High Licking/Grooming (84th percentile) | 50 μg/kg BPA | 16.4357 +/− 17.3262 | 0.9486 | 0.3490 | |
50 μg/kg Mixed BP | 6.1633 +/− 17.7028 | 0.3482 | 0.7297 | ||
150 μg/kg Mixed BP | 14.0685 +/− 17.8738 | 0.7871 | 0.4362 | ||
Percent Correct Trials in Attentional Set Shifting Task (Males) | Low Nest Attendance (16th percentile) | 50 μg/kg BPA | −8.9412 +/− 4.9007 | −1.8245 | 0.0766 |
50 μg/kg Mixed BP | 3.0964 +/− 4.1020 | 0.7549 | 0.4554 | ||
150 μg/kg Mixed BP | −0.1752 +/− 4.1374 | −0.0424 | 0.9665 | ||
Mid Nest Attendance (50th percentile) | 50 μg/kg BPA | −3.4508 +/− 3.3205 | −1.0392 | 0.3058 | |
50 μg/kg Mixed BP | 2.1978 +/− 2.9830 | 0.7368 | 0.4662 | ||
150 μg/kg Mixed BP | 3.2182 +/− 2.9835 | 1.0787 | 0.2881 | ||
High Nest Attendance (84th percentile) | 50 μg/kg BPA | 4.4064 +/− 4.2295 | 1.0418 | 0.3046 | |
50 μg/kg Mixed BP | 0.9119 +/− 4.3840 | 0.2080 | 0.8364 | ||
150 μg/kg Mixed BP | 8.0746 +/− 4.8408 | 1.6680 | 0.1042 | ||
Trials to Reach Criterion in Attentional Set Shifting Task (Females) | Low Nest Attendance (16th percentile) | 50 μg/kg BPA | 32.1010 +/− 19.4303 | 1.6521 | 0.1083 |
50 μg/kg Mixed BP | 8.7079 +/− 15.8739 | 0.5486 | 0.5871 | ||
150 μg/kg Mixed BP | 41.9213 +/− 18.8537 | 2.2235 | 0.0334 | ||
Mid Nest Attendance | 50 μg/kg BPA | 3.3268 +/− 13.3524 | 0.2492 | 0.8048 | |
50 μg/kg Mixed BP | −1.5408 +/− 11.7130 | −0.1315 | 0.8962 | ||
150 μg/kg Mixed BP | 7.3566 +/− 12.5510 | 0.5861 | 0.5619 | ||
High Nest Attendance (84th percentile) | 50 μg/kg BPA | −35.7009 +/− 17.3232 | −2.0609 | 0.0475 | |
50 μg/kg Mixed BP | −15.4417 +/− 17.5670 | −0.8790 | 0.3859 | ||
150 μg/kg Mixed BP | −39.5251 +/− 22.8893 | −1.7268 | 0.0938 | ||
Time Spent in Center of Open Field (Males) | Low Nest Attendance (16th percentile) | 50 μg/kg BPA | 35.1964 +/− 19.6657 | 1.7897 | 0.0775 |
50 μg/kg Mixed BP | 47.2734 +/− 19.1989 | 2.4623 | 0.0161 | ||
150 μg/kg Mixed BP | 5.6697 +/− 21.4596 | 0.2642 | 0.7923 | ||
Mid Nest Attendance (50th percentile) | 50 μg/kg BPA | −18.4510 +/− 14.2794 | −1.2921 | 0.2002 | |
50 μg/kg Mixed BP | −26.1659 +/− 14.0203 | −1.8663 | 0.0659 | ||
150 μg/kg Mixed BP | −28.6993 +/− 14.0125 | −2.0481 | 0.044 | ||
High Nest Attendance (84th percentile) | 50 μg/kg BPA | −69.0385 +/− 21.0396 | −3.2814 | 0.0016 | |
50 μg/kg Mixed BP | −95.4167 +/− 21.6009 | −4.4173 | < 0.0001 | ||
150 μg/kg Mixed BP | −61.1081 +/− 23.6794 | −2.5806 | 0.0118 |
p < 0.10; p < 0.05