Points | |
---|---|
I. ECG (12‐lead/ambulatory) | |
A. Spontaneous type 1 Brugada ECG pattern at nominal or high leads | 3.5 |
B. Fever‐induced type 1 Brugada ECG pattern at nominal or high leads | 3 |
C. Type 2 or 3 Brugada ECG pattern that converts with provocative drug challenge | 2 |
*Only award points once for the highest score within this category. One item from this category must apply. | |
II. Clinical history* | |
A. Unexplained cardiac arrest or documented VF/ polymorphic VT | 3 |
B. Nocturnal agonal respirations | 2 |
C. Suspected arrhythmic syncope | 2 |
D. Syncope of unclear mechanism/unclear etiology | 1 |
E. Atrial flutter/fibrillation in patients <30 years without alternative etiology | 0.5 |
*Only award points once for the highest score within this category. | |
III. Family history | |
A. First‐ or second‐degree relative with definite BrS | 2 |
B. Suspicious SCD (fever, nocturnal, Brugada aggravating drugs) in a first‐ or second‐degree relative | 1 |
C. Unexplained SCD <45 years in first‐ or second‐degree relative with negative autopsy | 0.5 |
*Only award points once for the highest score within this category. | |
IV. Genetic test result | |
A. Probable pathogenic mutation in BrS susceptibility gene | 0.5 |
Score (requires at least 1 ECG finding) | |
≥3.5 points: Probable/definite BrS | |
2–3 points: Possible BrS | |
<2 points: non‐diagnostic |
Abbreviations: BrS, Brugada syndrome; SCD, sudden cardiac death; VF, ventricular fibrillation; VT, ventricular tachycardia.