Table 1. Effects of N-acetyl-1-cysteine (NAC) on liver and kidney function tests in adult male albino Wistar rats exposed to penconazole (PEN).
| Group | AST (U/L) | ALT (U/L) | Creatinine (mg/dL) | Urea (mg/dL) |
|---|---|---|---|---|
| NC | 69.66 ± 1.16# | 24.70 ± 0.82# | 0.72 ± 0.01# | 25.18 ± 0.56 |
| PEN | 114.05 ± 4.79* | 51.35 ± 1.46* | 1.62 ± 0.02* | 57.36 ±0.60* |
| PEN+NAC | 86.20 ± 2.15*# | 38.24 ± 1.55*# | 0.85 ± 0.01# | 38.51 ± 0.45*# |
| NAC | 71.23 ± 1.52# | 27.12 ± 0.67# | 0.68 ± 0.01# | 27.94 ± 0.35# |
1
Data are presented as mean ± standard error of the mean (n = 6)
#
significantly different to control group
*
significantly different to PEN group; AST – aspartate aminotransferase; ALT – alanine aminotransferase; NC – normal control group