Table 3.
Subgroup analysis of the associations between NLR and mortality among diabetes
| Characteristics | Lower NLR (≤ 3.48) | Higher NLR# | p# | p interaction | Higher NLR* | p* | p interaction |
|---|---|---|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | ||||||
| Age, y | 0.704 | 0.085 | |||||
| < 60 | 1 | 2.28 (1.15–4.51) | 0.018 | 1.96 (0.55–6.95) | 0.29 | ||
| ≥ 60 | 1 | 1.99 (1.58–2.51) | < 0.0001 | 2.97 (1.99–4.42) | < 0.0001 | ||
| Sex | 0.752 | 0.21 | |||||
| Female | 1 | 2.08 (1.45–3.00) | < 0.0001 | 2.54 (1.40–4.58) | 0.002 | ||
| Male | 1 | 2.03 (1.57–2.63) | < 0.0001 | 3.46 (2.18–5.50) | < 0.0001 | ||
| Smoking status | 0.888 | 0.734 | |||||
| Never | 1 | 2.16 (1.49–3.12) | < 0.0001 | 2.72 (1.49–4.99) | 0.001 | ||
| Former/current | 1 | 2.04 (1.58–2.64) | < 0.0001 | 3.06 (1.86–5.02) | < 0.0001 | ||
| Drinking status | 0.748 | 0.733 | |||||
| Never | 1 | 2.21 (1.28–3.80) | 0.004 | 3.47 (1.31–9.18) | 0.012 | ||
| Former/mild/moderate/heavy | 1 | 2.03 (1.60–2.56) | < 0.0001 | 2.84 (1.86–4.35) | < 0.0001 | ||
| Hypertension | 0.597 | 0.622 | |||||
| No | 1 | 2.10 (1.32–3.33) | 0.002 | 5.09 (2.11–12.32) | < 0.001 | ||
| Yes | 1 | 2.06 (1.60–2.65) | < 0.0001 | 2.83 (1.88–4.27) | < 0.0001 |
#All-cause mortality; *cardiovascular mortality. HRs were adjusted for adjusted for age, sex, race, BMI, smoking, drinking, hypertension, HDL, LDL, TG, TC, HbA1c, education level, family income-to-poverty ratio, and eGFR