Table 1.
Characteristics of index patients with coexistent hypothyroidism and hyponatremia
| Characteristics | Total | Survive | Mortality | P-value | |||
|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | ||
| Overall | 3,140 | 3,069 | 97.74 | 71 | 2.26 | ||
| Gender | 0.717 | ||||||
| Male | 1,346 | 42.87 | 1,314 | 42.82 | 32 | 45.07 | |
| Female | 1,794 | 57.13 | 1,755 | 57.18 | 39 | 54.93 | |
| Age (yrs) | 72.58 ± 14.73 | 72.42 ± 14.77 | 79.71 ± 10.48 | <0.001 | |||
| Age group (yrs) | 0.013 | ||||||
| 0–4 | 9 | 0.29 | 9 | 0.29 | 0 | 0.00 | |
| 5–14 | 13 | 0.41 | 13 | 0.42 | 0 | 0.00 | |
| 15–24 | 13 | 0.41 | 13 | 0.42 | 0 | 0.00 | |
| 25–34 | 44 | 1.40 | 44 | 1.43 | 0 | 0.00 | |
| 35–44 | 66 | 2.10 | 66 | 2.15 | 0 | 0.00 | |
| 45–54 | 205 | 6.53 | 204 | 6.65 | 1 | 1.41 | |
| 55–64 | 417 | 13.28 | 411 | 13.39 | 6 | 8.45 | |
| 65–74 | 731 | 23.28 | 717 | 23.36 | 14 | 19.72 | |
| 75–84 | 1,093 | 34.81 | 1,068 | 34.80 | 25 | 35.21 | |
| ≧85 | 549 | 17.48 | 524 | 17.07 | 25 | 35.21 | |
| Low-income | 0.575 | ||||||
| Without | 3,064 | 97.58 | 2,994 | 97.56 | 70 | 98.59 | |
| With | 76 | 2.42 | 75 | 2.44 | 1 | 1.41 | |
| Catastrophic illness | <0.001 | ||||||
| Without | 2,660 | 84.71 | 2,613 | 85.14 | 47 | 66.20 | |
| With | 480 | 15.29 | 456 | 14.86 | 24 | 33.80 | |
| DM | 0.515 | ||||||
| Without | 2,628 | 83.69 | 2,566 | 83.61 | 62 | 87.32 | |
| With | 512 | 16.31 | 503 | 16.39 | 9 | 12.68 | |
| Disorders of adrenal glands | 0.225 | ||||||
| Without | 2,699 | 85.96 | 2,634 | 85.83 | 65 | 91.55 | |
| With | 441 | 14.04 | 435 | 14.17 | 6 | 8.45 | |
| Endocrine dysfunction | 0.879 | ||||||
| Without | 3,139 | 99.97 | 3,068 | 99.97 | 71 | 100.00 | |
| With | 1 | 0.03 | 1 | 0.03 | 0 | 0.00 | |
| HTN | <0.001 | ||||||
| Without | 2,513 | 80.03 | 2,445 | 79.67 | 68 | 95.77 | |
| With | 627 | 19.97 | 624 | 20.33 | 3 | 4.23 | |
| IHD | 0.802 | ||||||
| Without | 2,943 | 93.73 | 2,877 | 93.74 | 66 | 92.96 | |
| With | 197 | 6.27 | 192 | 6.26 | 5 | 7.04 | |
| HF | 0.068 | ||||||
| Without | 2,955 | 94.11 | 2,892 | 94.23 | 63 | 88.73 | |
| With | 185 | 5.89 | 177 | 5.77 | 8 | 11.27 | |
| CKD | 0.555 | ||||||
| Without | 3,001 | 95.57 | 2,934 | 95.60 | 67 | 94.37 | |
| With | 139 | 4.43 | 135 | 4.40 | 4 | 5.63 | |
| COPD | 0.376 | ||||||
| Without | 2,883 | 91.82 | 2,820 | 91.89 | 63 | 88.73 | |
| With | 257 | 8.18 | 249 | 8.11 | 8 | 11.27 | |
| Asthma | 0.395 | ||||||
| Without | 3,109 | 99.01 | 3,038 | 98.99 | 71 | 100.00 | |
| With | 31 | 0.99 | 31 | 1.01 | 0 | 0.00 | |
| Mental disorders | 0.321 | ||||||
| Without | 2,945 | 93.79 | 2,876 | 93.71 | 69 | 97.18 | |
| With | 195 | 6.21 | 193 | 6.29 | 2 | 2.82 | |
| Disorder of thyroid | - | ||||||
| Without | 3,140 | 100.00 | 3,069 | 100.00 | 71 | 100.00 | |
| With | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | |
| Diseases of the nervous system | 0.796 | ||||||
| Without | 2,755 | 87.74 | 2,692 | 87.72 | 63 | 88.73 | |
| With | 385 | 12.26 | 377 | 12.28 | 8 | 11.27 | |
| Cardiac dysrhythmias | 0.022 | ||||||
| Without | 2,985 | 95.06 | 2,922 | 95.21 | 63 | 88.73 | |
| With | 155 | 4.94 | 147 | 4.79 | 8 | 11.27 | |
| BPH | 0.625 | ||||||
| Without | 3,097 | 98.63 | 3,026 | 98.60 | 71 | 100.00 | |
| With | 43 | 1.37 | 43 | 1.40 | 0 | 0.00 | |
| Cardiomyopathy | 0.761 | ||||||
| Without | 3,136 | 99.87 | 3,065 | 99.87 | 71 | 100.00 | |
| With | 4 | 0.13 | 4 | 0.13 | 0 | 0.00 | |
| Sickle-cell disease | - | ||||||
| Without | 3,140 | 100.00 | 3,069 | 100.00 | 71 | 100.00 | |
| With | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | |
| Liver cirrhosis | 0.627 | ||||||
| Without | 3,092 | 98.47 | 3,021 | 98.44 | 71 | 100.00 | |
| With | 48 | 1.53 | 48 | 1.56 | 0 | 0.00 | |
| Operations on bone marrow and spleen | 0.792 | ||||||
| Without | 3,137 | 99.90 | 3,066 | 99.90 | 71 | 100.00 | |
| With | 3 | 0.10 | 3 | 0.10 | 0 | 0.00 | |
| Season | 0.306 | ||||||
| Spring (Mar-May) | 729 | 23.22 | 713 | 23.23 | 16 | 22.54 | |
| Summer (Jun-Aug) | 762 | 24.27 | 745 | 24.28 | 17 | 23.94 | |
| Autumn (Sep-Nov) | 812 | 25.86 | 799 | 26.03 | 13 | 18.31 | |
| Winter (Dec-Feb) | 837 | 26.66 | 812 | 26.46 | 25 | 35.21 | |
| Location | 0.448 | ||||||
| Northern Taiwan | 1,254 | 39.94 | 1,227 | 39.98 | 27 | 38.03 | |
| Middle Taiwan | 785 | 25.00 | 764 | 24.89 | 21 | 29.58 | |
| Southern Taiwan | 937 | 29.84 | 916 | 29.85 | 21 | 29.58 | |
| Eastern Taiwan | 149 | 4.75 | 148 | 4.82 | 1 | 1.41 | |
| Outlets islands | 15 | 0.48 | 14 | 0.46 | 1 | 1.41 | |
| Urbanization level | 0.184 | ||||||
| 1 (The highest) | 986 | 31.40 | 969 | 31.57 | 17 | 23.94 | |
| 2 | 1,403 | 44.68 | 1,372 | 44.71 | 31 | 43.66 | |
| 3 | 199 | 6.34 | 195 | 6.35 | 4 | 5.63 | |
| 4 (The lowest) | 552 | 17.58 | 533 | 17.37 | 19 | 26.76 | |
| Level of care | <0.001 | ||||||
| Hospital center | 1,164 | 37.07 | 1,148 | 37.41 | 16 | 22.54 | |
| Regional hospital | 1,437 | 45.76 | 1,407 | 45.85 | 30 | 42.25 | |
| Local hospital | 539 | 17.17 | 514 | 16.75 | 25 | 35.21 | |
| Surgery | 0.769 | ||||||
| Without | 3,006 | 95.73 | 2,937 | 95.70 | 69 | 97.18 | |
| With | 134 | 4.27 | 132 | 4.30 | 2 | 2.82 | |
| Length of stay (days) | 13.14 ± 15.41 | 12.93 ± 14.52 | 22.25 ± 36.24 | <0.001 | |||
| Length of days groups | 0.010 | ||||||
| ≦30 | 2,899 | 92.32 | 2,840 | 92.54 | 59 | 83.10 | |
| > 30 | 241 | 7.68 | 229 | 7.46 | 12 | 16.90 | |
| Medical cost (NT$) | 58,211.36 ± 91,002.51 | 56,972.80 ± 88,847.38 | 111,748.15 ± 149,710.89 | <0.001 | |||
| Repeated inpatient | 0.370 | ||||||
| Without | 2,731 | 86.97 | 2,672 | 87.06 | 59 | 83.10 | |
| With | 409 | 13.03 | 397 | 12.94 | 12 | 16.90 | |
p-value (categorical variable: Chi-square test/Fisher’s exact test; continuous variable: t-test)