Table 1.
Characteristics of the patients at ICU admission.
| ICU control group (n = 33) | Infection group (n = 29) | Septic nonshock group (n = 40) | Septic shock group (n = 94) | P value | |
|---|---|---|---|---|---|
| Mean age (years) | 63 (46–70) | 57 (47–67) | 66 (54–76) | 66 (56–72) | 0.060 |
| Male sex (n, %) | 18 (54.5) | 23 (79.3) | 23 (57.5) | 66 (70.2) | 0.190 |
| APACHE II score | 13 (10–15) | 14 (8–17) | 17 (16–24)a,c | 20 (17–29)a,b,c | <0.001 |
| SOFA score | 0 (0–0) | 0 (0–2) | 9 (4–12)a,c | 13 (10–15)a,b,c | <0.001 |
| BMI (kg/m2) | 23 (21–27) | 24 (22–26) | 23 (21–24) | 23 (20–25) | 0.264 |
| Life-support | |||||
| MV (hour) | 11 (4–73) | 22 (10–116) | 42 (8–157) | 65 (12–216)c | 0.026 |
| NE (μg/kg/minute) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0.22 (0.09–0.56)a,b,c | <0.001 |
| Inotropes (n, %) | 3 (9.1 | 4 (13.8) | 10 (25.6) | 24 (25.5) | 0.324 |
| CRRT (n, %) | 3 (9.1) | 3 (10.3) | 7 (17.5) | 20 (21.3) | 0.519 |
| Corticoids (n, %) | 5 (15.2% | 4 (13.8) | 4 (13.79) | 21 (22.3) | 0.253 |
| HR (beats/minute) | 85 (70–94) | 90 (80–101) | 95 (83–110) | 105 (90–118)a,c | <0.001 |
| MAP (mmHg) | 95 (87–101) | 92 (86–102) | 85 (79–95)c | 82 (72–94)c | <0.001 |
| Infection source (n, %) | |||||
| Abdominal | 10 (14.9) | 11 (16.4) | 12 (17.9) | 34 (50.7%)a,c | 0.030 |
| Pulmonary | 6 (12.2) | 6 (12.2) | 5 (10.2%a,c | 32 (65.3%)a,b,c | 0.020 |
| Blood (including catheter related) | 2 (13.3) | 0 (0) | 7 (46.7)a | 6 (40)a,b,c | <0.001 |
| Skin, bone, or soft tissue | 0 (0) | 1 (12.5) | 2 (25)a,,c | 5 (62.5)a,b,c | 0.011 |
| Others | 2 (8.7) | 6 (26.1) | 7 (30.4) | 8 (34.8) | 0.370 |
The data are shown as the mean ± standard deviation, n (%), or median (interquartile range). aP < 0.05 compared with the infection group; bP < 0.05 compared with the sepsis nonshock group; cP < 0.05 compared with the ICU control group.
ICU, intensive care unit; APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment; BMI, body mass index; MV, mechanical ventilation; NE, norepinephrine; CRRT, continuous renal replacement therapy; HR, heart rate; MAP, mean arterial blood pressure.